New POEM technique aims to cut reflux risk in achalasia patients

NCT ID NCT07178821

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 24 times

Summary

This study compares two versions of a minimally invasive surgery (POEM) for achalasia, a condition that makes swallowing difficult. The standard surgery often leads to severe acid reflux. The modified version tries to preserve certain muscle fibers to reduce that risk. About 120 adults with achalasia will be randomly assigned to one of the two procedures and followed for a year to see which causes less reflux.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, Irvine - UCI Medical Center

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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