Can a diet and lifestyle program replace acid reflux pills after achalasia surgery?

NCT ID NCT07620899

Ongoing Disease control Sponsor: Asian Institute of Gastroenterology, India Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a structured program of dietary changes, lifestyle adjustments, and nutrient correction can reduce reflux symptoms in patients who had POEM surgery for achalasia. Many patients develop GERD after POEM and rely on long-term acid-reducing medications. The trial compares this program to standard care in 166 adults, with the goal of improving quality of life and reducing medication dependence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: structured diet and lifestyle program (dietary counseling, micronutrient correction, H. pylori treatment, lifestyle optimization)
What this could lead to: If it works, this program could help many patients reduce or stop their acid-reducing medications and improve their quality of life after POEM surgery.
What could go wrong: This is a relatively small, early-stage trial (166 participants) testing a non-drug intervention, so results may not apply broadly. The program requires strict adherence, and some patients may not benefit or may still need medication.

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Conditions

The condition(s) this trial relates to.

Esophageal Achalasia gastroesophageal reflux disease idiopathic achalasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACHALASIA CARDIA GERD (GASTROESOPHAGEAL REFLUX DISEASE)

Contacts and locations

Locations

Asian Institute of Gastroenterology

Hyderabad, Telangana, 500032, India

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