Fat cells injected into esophagus could tame reflux without surgery
NCT ID NCT07638423
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether injecting a patient's own fat-derived cells into the lower esophagus is safe and feasible for treating GERD that doesn't respond well to medication. Fifteen adults with chronic acid reflux will undergo a minimally invasive endoscopic procedure. The goal is to see if this cell therapy can strengthen the anti-reflux barrier and help patients reduce or stop daily acid-reflux pills.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
patient's own fat-derived cells (stromal vascular fraction)
What this could lead to
If it works, this could offer a minimally invasive, cell-based alternative to surgery for GERD, potentially reducing or eliminating the need for daily acid-reflux medication.
What could go wrong
This is a very early, small pilot study with only 15 participants, so results may not apply to everyone. The procedure is new and risks like bleeding, infection, or no improvement are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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