Asian Institute Of Gastroenterology, India

This pilot study tests a new procedure for people with Crohn's disease who have anal fistulas that haven't healed with standard treatments. Doctors take a small amount of fat from the patient's belly, process it mechanically in the same surgery, and inject it into the fistula tra…

This study compares two methods of preventing bleeding during a procedure called POEM, used to treat swallowing disorders. The standard method uses carbon dioxide gas, while the new method uses water to help seal blood vessels. Researchers will enroll 120 adults to see if the wat…

This phase 3 trial tests whether taking pancreatic enzyme capsules can help people who have lost significant weight after a severe bout of pancreatitis. The study will enroll 140 adults with more than 50% pancreatic damage and at least 5% weight loss. Participants will receive ei…

This study tests whether a newer acid-reducing drug, Vonaprazan, heals acid reflux better than the standard drug Esomeprazole in people who had POEM surgery for achalasia. About 300 adults with moderate to severe esophagitis will take one of the two drugs for 8 weeks. The goal is…

This study compares two doses of vonaprazan (10 mg and 20 mg) with esomeprazole 40 mg for healing moderate to severe reflux esophagitis (grades B, C, or D) over 8 weeks. About 414 adults with GERD symptoms for at least 4 weeks will be randomly assigned to one of the three groups.…

This study tests whether an AI-enabled robotic stapler can reduce complications like leaks after colorectal cancer surgery compared to a standard stapler. About 200 adults undergoing planned robotic or laparoscopic surgery for non-metastatic colorectal cancer will be enrolled. Th…

This trial compares removing a metal stent at 2 weeks (with a plastic stent placed) versus the usual 4 weeks (without a plastic stent) in adults with walled-off pancreatic necrosis. The goal is to see if earlier removal lowers the chance of fluid collections coming back or needin…

This study looks at whether a weight-loss procedure called Endoscopic Sleeve Gastroplasty (ESG), combined with healthy eating and exercise, can improve obstructive sleep apnea (OSA) in people with obesity. About 74 adults with moderate to severe OSA will be randomly assigned to r…

This study tests whether a machine learning model can accurately predict gallstones in the bile duct, potentially reducing the need for invasive endoscopic ultrasound or MRI. Researchers will enroll 1,000 adults with a moderate chance of having gallstones. If the model works well…

This study tests whether rinsing the bile duct opening with cold water, in addition to standard rectal indomethacin, can better prevent pancreatitis after ERCP—a common procedure to treat bile or pancreas issues. About 150 adults in India will be randomly assigned to get either t…

This study investigates why pain from chronic pancreatitis persists even after treating the pancreas. Researchers will use brain scans and psychological tests to see if the brain itself becomes sensitized to pain. By comparing patients with painful chronic pancreatitis to those w…

This study looks at medical records of 514 adults in India with acute cholangitis (a bile duct infection and blockage) who had a drainage procedure. The goal is to create a new composite index that combines factors like death, need for organ support, ICU stay, complications, hosp…

This study looks at 200 adults to compare acid reflux-related damage in two groups: people who had a procedure called POEM for achalasia (a swallowing disorder) and people without any swallowing problems. Researchers will use endoscopy and acid monitoring to see if the pattern of…

This study looks at how much energy, water, and waste are used during different types of bowel imaging tests for people with ulcerative colitis or Crohn's disease. The goal is to see if a simple, non-invasive ultrasound can be a greener alternative to colonoscopy and CT scans. Ab…

This study tests an artificial intelligence tool that helps doctors see blood vessels during endoscopic procedures for achalasia or tumors. The AI aims to reduce the risk of bleeding and injury by spotting vessels faster and more accurately. Twenty participants will be enrolled t…

This study looks at 500 adults with acute pancreatitis to find out how often blood clots form in the veins around the pancreas (splanchnic veins). Researchers will also check if these clots are linked to more severe pancreatitis. Participants will have imaging scans to detect clo…

This study compares the carbon footprint of two tests used to diagnose gallstones: endoscopic ultrasound (EUS) and magnetic resonance cholangiopancreatography (MRCP). Both are equally accurate, but MRCP uses more energy and larger machines. Researchers will measure the total gree…