Water vs. gas: can a simple change make a key esophagus surgery safer?

NCT ID NCT07575295

Recruiting now Disease control Sponsor: Asian Institute of Gastroenterology, India Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two methods of preventing bleeding during a procedure called POEM, used to treat swallowing disorders. The standard method uses carbon dioxide gas, while the new method uses water to help seal blood vessels. Researchers will enroll 120 adults to see if the water technique reduces the need for extra tools to stop bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Underwater preventive coagulation (electrosurgical technique using water as conductive medium)
What this could lead to: If successful, this technique could make POEM safer and faster by reducing bleeding and the need for extra instruments.
What could go wrong: This is a small, early-stage trial (120 participants) testing a procedural tweak, not a new drug. The benefit may be modest or not reproducible in other centers.

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Conditions

The condition(s) this trial relates to.

achalasia dyskinesia of esophagus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VESSEL PUNCTURE SITE REACTION

Contacts and locations

Locations

Asian Institute of Gastroenterology Hospital
RECRUITING

Hyderabad, Telangana, 500082, India

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