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Brain scans reveal hidden pain pathways in chronic pancreatitis

NCT ID NCT07707609

Knowledge-focused Sponsor: Asian Institute of Gastroenterology, India Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study investigates why pain from chronic pancreatitis persists even after treating the pancreas. Researchers will use brain scans and psychological tests to see if the brain itself becomes sensitized to pain. By comparing patients with painful chronic pancreatitis to those without pain and to healthy volunteers, they hope to uncover new targets for pain relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could identify brain-based markers of pain in chronic pancreatitis, leading to more personalized and effective pain treatments.
What could go wrong
This is an observational study, not a treatment trial. It may not directly lead to new therapies, and the findings might not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult participants aged 18-60 years with diagnosed chronic pancreatitis and healthy controls

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with CP confirmed by CECT, MRCP, or EUS based on Cambridge or Rosemont criteria. * Age 18-60 years. * Both genders Exclusion Criteria: * Recent episode of acute pancreatitis or ongoing pain (VAS \>5). * Pancreatic cancer and other significant comorbidities. * Recent use of antidepressants, anxiolytics, high-potency opioids, or neuromodulators. * Pregnancy and lactation. * Inability to give informed consent.

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Conditions

The condition(s) this trial relates to.

agnosia chronic pancreatitis Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pancreatitis Pain management

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Asian Institute of Gastroenterology

    RECRUITING

    Hyderabad, Telangana, 500032, India

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