Can a simple cone test predict fall risk in multiple sclerosis?
NCT ID NCT07786987
First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time
Summary
This study evaluates whether the Cone Evasion Walk Test—a walking task that involves stepping around cones—is a reliable and valid way to assess balance, obstacle avoidance, and fall risk in people with multiple sclerosis (MS). Researchers will measure how consistent the test results are across repeated sessions and compare them with established mobility and balance measures. The study includes 50 adults with MS who can walk independently, aiming to determine if this test is a useful clinical tool for this population.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Cone Evasion Walk Test (a performance-based walking assessment)
- What this could lead to
- If reliable and valid, this test could become a standard tool to assess walking and fall risk in people with multiple sclerosis, helping guide rehabilitation.
- What could go wrong
- This is a small, early-stage study focused on measurement properties, not treatment outcomes. The test may not prove reliable or valid in this population, and results may not generalize beyond the study group.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Oct 2026
An estimate. Start dates often move.
- Expected to finish
-
Sep 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of adults with a confirmed diagnosis of multiple sclerosis who meet the predefined eligibility criteria. Participants will be recruited from individuals with multiple sclerosis and will undergo the Cone Evasion Walk Test and standardized clinical assessments to investigate the reliability and validity of the test in this population.
- Ages
-
18 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Confirmed diagnosis of Multiple Sclerosis according to the 2017 revised McDonald criteria Age between 18 and 65 years Expanded Disability Status Scale (EDSS) score ≤6.0 Clinically stable, with no MS relapse within the previous 30 days Able to walk at least 10 meters independently, with or without a unilateral assistive device Able to understand and follow study instructions Willing and able to provide written informed consent Exclusion Criteria: MS relapse within the previous 30 days Cognitive impairment that prevents understanding of instructions or completion of the study assessments Co-existing orthopedic, cardiovascular, vestibular, or neurological conditions other than MS that significantly affect gait, balance, or safe performance of the CEW Severe uncorrected visual impairment that may interfere with obstacle detection Wheelchair-dependent mobility or requirement for bilateral walking aids Change in MS-related medication within the previous 30 days Participation in a structured exercise or rehabilitation program within the previous 4 weeks
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Function are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Erciyes University Faculty of Medicine Hospitals
Erciyes, Kayseri, 38039, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Simulator-Based assessment of driving performance in patients with Parkinson's disease and multiple sclerosis
- Contrasting chronic inflammation and neurodegeneration using the human amniotic mesenchymal cell secretome as an innovative therapeutic strategy
- VIGIP-SEP2: evaluation of the impact of the training of patients by nurses on the adverse drug reaction reporting by RRMS patient via a mobile application: a randomized real-life study
- Light therapy may soothe cesarean wounds and cut painkiller use
- Five-second sprints on a bike: a new test for multiple sclerosis symptoms
- A new way to gauge balance training intensity in MS?