Asian Institute Of Gastroenterology, India

This trial compares fungal-based pancreatic enzymes to standard pig-derived enzymes in people with chronic pancreatitis and digestive insufficiency. Participants take either the fungal or porcine enzyme for 12 weeks to see if the fungal version works just as well. The goal is to …

This study looks at whether injecting a patient's own fat-derived cells can help close abnormal connections (fistulas) in the gut that won't heal with standard treatments. Researchers will track 50 adults to see what factors predict successful closure. The goal is to understand w…

This early study tests a new device called TIES® that is surgically implanted in the abdomen to help people with a permanent ileostomy or colostomy control when they empty their bowels. Ten adults will receive the implant during a stoma revision surgery and be followed for 16 wee…

This study tests a drug called esomeprazole, given through an IV, to prevent stress ulcers and acid reflux in 50 adults recovering from surgery in the intensive care unit (ICU). The goal is to see if it can keep stomach acid low enough to reduce the risk of bleeding. Participants…

This study looks at adults hospitalized with a severe flare of ulcerative colitis that didn't get better with IV steroids. It compares taking two drugs together (infliximab and tofacitinib) versus taking just one of them. The goal is to see if the combo leads to faster symptom re…

This study tests whether taking pancreatic enzyme pills can help people who have lost significant weight after a severe bout of pancreatitis regain a healthier body weight. The trial will enroll 188 adults aged 18-60 who have lost at least 10% of their body weight due to the dise…

This study will compare two procedures—balloon dilation and per oral endoscopic myotomy (POEM)—in 70 children aged 3–17 with achalasia cardia, a condition where the esophagus can't push food into the stomach. Children will be randomly assigned to one procedure, and if it fails, t…

This study compares two ways of doing a surgery called POEM for people with type II achalasia, a condition where the esophagus has trouble moving food into the stomach. The standard method uses a long tunnel under the lining of the esophagus, but this can cause bad acid reflux af…

This observational study aims to determine what healthy liver tissue looks like on two new types of endoscopic ultrasound (EUS) measurements: attenuation imaging (ATI) and shear wave elastography (SWE). Researchers will enroll 100 adults who already need a diagnostic EUS for non-…

This study will examine 4,000 adults aged 40 and older in India using high-definition endoscopy to find early stomach cancer and precancerous changes. Participants are people already scheduled for an upper GI endoscopy due to digestive symptoms. The goal is to learn how common th…

This trial compares two techniques used when standard bile duct access fails during ERCP: pre-cut sphincterotomy and the double guidewire technique. Researchers will enroll 840 adults with difficult bile duct cannulation to see which method is safer and more successful. The goal …

This study will track over 2,300 patients in India who undergo ERCP, a procedure to treat bile duct problems. The goal is to measure how often pancreatitis occurs after the procedure and how severe it is. By following standard safety steps, researchers hope to find ways to lower …

This study will test whether a computer model can accurately predict the chance of finding precancerous colon polyps in 1,000 Indian adults undergoing a routine colonoscopy. The model uses basic health information like age, sex, and lifestyle factors. If it works well, it could h…

This pilot study will check if simethicone, a medicine used to reduce gas during endoscopy, makes it harder to detect H. pylori bacteria. About 100 adults with a positive H. pylori test will take simethicone or a placebo before their procedure. The goal is to see if the drug lowe…