Can enzyme pills help pancreatitis patients regain lost weight?

NCT ID NCT07211568

Not yet recruiting Disease control Sponsor: Asian Institute of Gastroenterology, India Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking pancreatic enzyme pills can help people who have lost significant weight after a severe bout of pancreatitis regain a healthier body weight. The trial will enroll 188 adults aged 18-60 who have lost at least 10% of their body weight due to the disease. Participants will receive either the enzyme pills or a placebo for 3 months, and researchers will track changes in BMI and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pancreatic enzyme replacement therapy (lipase 25000 IU)
What this could lead to: If it works, this could offer a way to help patients with severe acute pancreatitis regain weight and improve their nutrition and quality of life.
What could go wrong: This is a relatively small early-phase trial, and the benefit may be modest or not statistically significant. The intervention only addresses nutrition, not the underlying pancreatic damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute necrotizing pancreatitis exocrine pancreatic insufficiency Pancreatitis, Acute Necrotizing

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE PANCREATITIS NECROTIZING NUTRITION ASSESSMENT

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