Can a shorter surgical tunnel fix swallowing without causing heartburn?

NCT ID NCT07325071

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two ways of doing a surgery called POEM for people with type II achalasia, a condition where the esophagus has trouble moving food into the stomach. The standard method uses a long tunnel under the lining of the esophagus, but this can cause bad acid reflux afterward. The new method uses a shorter tunnel and focuses the cut only at the tight muscle. The trial will enroll 636 adults and track how well each method relieves symptoms and how often it causes reflux.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Procedure: Peroral Endoscopic Myotomy (POEM) with short submucosal tunnel
What this could lead to
If successful, this could offer a safer surgical option for achalasia patients with less post-surgery acid reflux and faster recovery.
What could go wrong
This is an early-stage trial with no results yet. The shorter tunnel might not relieve swallowing symptoms as well as the standard approach.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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