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Enzyme pills could help severe pancreatitis patients regain weight

NCT ID NCT07441824

Recruiting now Disease control Sponsor: Asian Institute of Gastroenterology, India Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether taking pancreatic enzyme capsules can help people who have lost significant weight after a severe bout of pancreatitis. The study will enroll 140 adults with more than 50% pancreatic damage and at least 5% weight loss. Participants will receive either the enzyme pills or a placebo for 3 months, and researchers will measure weight change and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
pancreatic enzyme capsules (lipase 25000 IU)
What this could lead to
If it works, this could provide a simple treatment to help patients with severe pancreatitis regain weight and improve their quality of life.
What could go wrong
This is a relatively small trial (140 people) and the main goal is weight gain, not survival or cure. The treatment may not work better than placebo, and some patients may have side effects from the enzymes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute necrotizing pancreatitis exocrine pancreatic insufficiency pancreatitis Pancreatitis, Acute Necrotizing

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE NECROTIZING PANCREATITIS PANCREATIC EXOCRINE INSUFFICIENCY

Contacts and locations

Locations

  • Asian Institute of Gastroenterology Hospitals, Gachibowli

    RECRUITING

    Hyderabad, Telangana, 500032, India

  • Asian Institute of Gastroenterology, Banjara Hills

    RECRUITING

    Hyderabad, Telangana, 500082, India

  • Gauhati Medical College

    RECRUITING

    Guwahati, Assam, 781032, India

  • ILS Hospital, Dum Dum

    RECRUITING

    Kolkata, West Bengal, 700080, India

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