New PET scan could spot leftover prostate cancer after targeted treatment
NCT ID NCT07568756
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial will test whether a special PET scan using Flotufolastat F18 can accurately detect any remaining prostate cancer after focal therapy (like cryotherapy or HIFU). About 60 men with prostate cancer who haven't had prior treatment will get the scan before and after their focal therapy. The results will be compared to standard MRI and biopsy to see if the PET scan is a reliable way to confirm successful treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Flotufolastat F18 (a radioactive tracer used in PET scans)
- What this could lead to
- If successful, this could provide a more accurate way to check if focal therapy has fully treated prostate cancer, potentially reducing the need for repeat biopsies.
- What could go wrong
- This is a small, early-phase study (60 participants) focused on diagnostic accuracy, not treatment. The tracer may not prove reliable enough to replace current methods, and results may not apply to all prostate cancer patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Chao Family Comprehensive Cancer Center, University of California, Irvine
Orange, California, 92868, United States
Contact Email: •••••@•••••
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