New PET scan could spot leftover prostate cancer after targeted treatment

NCT ID NCT07568756

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial will test whether a special PET scan using Flotufolastat F18 can accurately detect any remaining prostate cancer after focal therapy (like cryotherapy or HIFU). About 60 men with prostate cancer who haven't had prior treatment will get the scan before and after their focal therapy. The results will be compared to standard MRI and biopsy to see if the PET scan is a reliable way to confirm successful treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Flotufolastat F18 (a radioactive tracer used in PET scans)

What this could lead to

If successful, this could provide a more accurate way to check if focal therapy has fully treated prostate cancer, potentially reducing the need for repeat biopsies.

What could go wrong

This is a small, early-phase study (60 participants) focused on diagnostic accuracy, not treatment. The tracer may not prove reliable enough to replace current methods, and results may not apply to all prostate cancer patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Chao Family Comprehensive Cancer Center, University of California, Irvine

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••