AI chatbot as a therapy buddy: new study tests ChatGPT for anxiety and depression

NCT ID NCT07225192

Not yet recruiting Symptom relief Sponsor: University of California, Irvine Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test if using an AI chatbot like ChatGPT can help people with generalized anxiety disorder or major depressive disorder who are already in regular therapy. Researchers plan to recruit 204 adults in the U.S. who are currently in individual therapy. Participants will use the chatbot as an extra tool alongside their usual treatment, and the study will track changes in anxiety and depression symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AI chatbot (like ChatGPT) used as an adjunct to therapy
What this could lead to: If it works, this could show that AI chatbots are a helpful extra tool for people already in therapy for anxiety or depression.
What could go wrong: This is an early study with no phase, so results are uncertain. The chatbot is not a replacement for therapy, and its effectiveness may vary. Privacy and reliance on AI are potential concerns.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

generalized anxiety disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GENERALIZED ANXIETY DISORDER (GAD) MAJOR DEPRESSIVE DISORDER

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Other studies related to the condition(s) this trial covers.