University Medical Center Groningen

This early-phase study tested a vaccine called DCP-001 in 17 people with a serious type of ovarian cancer who had already completed standard treatment. The goal was to see if the vaccine is safe and can boost the immune system to recognize and fight cancer cells. Results will hel…

This study tested whether a low dose of digoxin, a very old and cheap heart drug, can help people with chronic heart failure. About 982 adults with heart failure and reduced pumping function took either digoxin or a placebo. The goal was to see if digoxin could reduce hospital st…

This study tested whether people with type 2 diabetes and early kidney disease can manage their medications from home. Twelve participants took empagliflozin and, if needed, added finerenone to lower protein in their urine. They measured their own blood pressure, weight, and coll…

This study tested a smartphone app called Compas-Y that teaches self-compassion to people with cancer who feel distressed. 28 adults who had finished cancer treatment used the app for 6 weeks. Researchers checked if the app was easy to use and if it improved well-being, self-comp…

This study tested a tool called MuSt-PC to help doctors and nurses better manage multiple symptoms in patients receiving palliative care. The goal was to see if the tool was easy to use and helpful for improving quality of life. 70 healthcare professionals participated, and the s…

This pilot study tested a tool called MuSt-PC that helps doctors and nurses make better decisions for adults with serious illnesses who are expected to live less than a year. The goal was to see if patients could complete the study assessments and if the tool helped manage multip…

This study checked over 4,000 ICU patients for undiagnosed diabetes and prediabetes using a blood test (HbA1c). It found that many patients have these conditions without knowing, and they may face higher risks of organ failure and death. The goal was to better understand how bloo…

This study looked at whether a certain type of immune cell (cytotoxic CD4+ T cells) is linked to fatigue in people with multiple sclerosis (MS). 34 adults with MS completed physical tasks and fatigue surveys, and researchers measured their immune cells. The goal was to better und…

This study looked at 807 adults with adrenal tumors found by chance during scans for other reasons. Researchers compared the standard approach of repeated CT scans with a single urine test to see which was more cost-effective for detecting cancer. The goal was to find a simpler, …

This study tested a new imaging technique to visualize PD-L1, a protein that helps tumors hide from the immune system, in people with esophageal cancer. Researchers gave 21 participants a fluorescent dye that attaches to PD-L1 and used a special camera during endoscopy to see whe…

This study tested whether special communication training for pharmacists and general practitioners helps them safely reduce or stop heart and diabetes medications in patients aged 75 and older. The training aimed to make it easier for healthcare providers to involve older patient…

This study explored how changes in healthcare during the COVID-19 pandemic (2020-2021) impacted the quality of life and experiences of over 5,000 Dutch patients who had surgery or another medical procedure. Researchers used focus groups and surveys to understand what mattered mos…

This study tested a computer model (Eleveld) to predict the right dose of propofol for sedation in 75 adults undergoing procedures. Researchers measured sedation depth and brain activity to see how well the model worked. The goal was to improve dosing accuracy, not to treat a dis…

This study followed 72 kidney and lung transplant patients for one year to see how their hand tremors changed over time. Tremors are a common side effect of the anti-rejection drugs (calcineurin inhibitors) that patients must take. Researchers measured tremor severity using spira…

This study tested whether using a 3D heart map during pulsed field ablation (a procedure to treat atrial fibrillation) helps doctors deliver more precise burns to the right spots. Thirty-two adults with AF were randomly assigned to get the procedure with or without the 3D map. Th…