University Medical Center Groningen

This early-stage study tested a vaccine called DCP-001 in 17 women with a serious type of ovarian cancer who had already completed standard treatment. The goal was to see if the vaccine is safe and can boost the immune system to recognize and fight cancer cells. Researchers measu…

This study tested whether using a 3D electroanatomic mapping system (FARAVIEW) during pulsed field ablation helps create more precise lesions in the pulmonary veins of people with atrial fibrillation. Thirty-two participants were randomly assigned to receive ablation with or with…

This study tested whether low doses of digoxin, an old and cheap heart drug, can reduce hospitalizations and death in 982 heart failure patients. Participants received either digoxin or a placebo pill. The goal is to see if keeping digoxin levels low in the blood improves outcome…

This study tested whether people with type 2 diabetes and kidney damage can safely participate in a clinical trial from home. Twelve participants took the drug empagliflozin, and depending on their response, some added or switched to finerenone. The goal was to see if remote data…

This study tested an 8-week program called STAIRS for people recovering from depression. The program combines group meetings with homework exercises to help improve personal recovery and daily functioning. 36 adults in the final phase of depression treatment took part. The goal w…

This study tested a smartphone app called Compas-Y, designed to help people with cancer manage emotional distress through self-compassion exercises. 28 adults who had finished cancer treatment and felt low well-being used the app for 6 weeks. Researchers measured changes in self-…

This pilot study tested a clinical decision-support system called MuSt-PC, designed to help doctors and nurses manage multiple symptoms in patients receiving palliative care. 44 adults with life-limiting illnesses and at least two moderate-to-severe symptoms participated. The stu…

This study looked at 583 children who had liver transplants and later developed narrowing or blockage of the liver artery. Researchers wanted to find out how common these problems are and what treatments work best. The goal is to improve care and outcomes for future patients.

This study looks at 250 people with atrial fibrillation who are having a hybrid ablation procedure. Researchers want to find out which factors—like clinical history, blood markers, and genetics—are linked to the procedure failing. The goal is to create a risk profile that helps d…

This study looked at 800 emergency ICU patients to see if simple checks and gut feelings from nurses and students can predict who will survive, just as well as complex scoring systems. The goal was to collect data and compare different prediction methods to find the easiest and m…

This study followed 122 COVID-19 patients who were in the ICU, along with their family members, for up to a year after leaving the hospital. Researchers measured physical health, mental well-being, and how well people returned to work and daily life. The goal was to learn about t…

This study looked at over 4,000 ICU patients to find out how many have undiagnosed diabetes or prediabetes. Researchers used a blood test (HbA1c) to check blood sugar control and tracked whether these conditions led to more organ failure or death. The goal is to better understand…

Fatigue is a major problem for people with multiple sclerosis (MS), but its cause is unknown and there is no good treatment. This completed study looked at 34 adults with MS to see if a type of immune cell (cytotoxic CD4+ T cells) is linked to how tired they feel. Researchers mea…

This study tested a new imaging method to see a protein called PD-L1 in esophageal tumors. PD-L1 levels may help predict if immunotherapy will work, but current biopsy tests are often inaccurate. Researchers gave 21 patients a fluorescent tracer that binds to PD-L1, then used a s…

This study tested whether special communication training for pharmacists and general practitioners helps them involve older patients in decisions to stop or lower medications for heart disease and diabetes. Researchers enrolled 310 patients aged 75 and older who were taking certa…

This study looked at 807 adults with adrenal tumors found by accident during scans for other reasons. Researchers compared the usual approach of repeat CT scans to a single urine steroid profile test to see which is more cost-effective for detecting cancer. The goal is to find a …

This study explored how changes in healthcare during the COVID-19 pandemic (2020-2021) impacted the quality of life and experiences of over 5,000 Dutch patients who had surgery or another medical procedure. Researchers first held focus groups to understand key themes, then create…

This study looked at whether healthcare workers would use a new tool called MuSt-PC to help manage symptoms in patients receiving palliative care. Researchers surveyed 70 doctors, specialists, and nurse practitioners about their intention to use the tool. The goal is to improve q…

This study tested whether a computer model (Eleveld model) can accurately predict how much propofol is needed for different levels of sedation during medical procedures. 75 adults receiving sedation were monitored using sedation scores and brain activity. The goal was to improve …

This study followed 72 kidney and lung transplant recipients for one year to see how hand tremors—a common side effect of anti-rejection drugs—change over time. Researchers used spiral drawings and wrist-worn accelerometers to measure tremor severity. The goal was to understand t…