Rigshospitalet, Denmark

This trial tests whether a gentler suction level (-2 cmH2O) on chest tubes after keyhole lung cancer surgery works as well as the standard stronger suction (-10 cmH2O). The goal is to see which setting allows tubes to be removed sooner and causes fewer complications. About 230 ad…

This study compared a new bone graft material (ABM/P-15) to the standard bone graft in 120 adults having surgery for spinal deformity. The goal was to see if the new graft leads to fewer additional surgeries and better bone healing. Patients were randomly assigned to receive eith…

This study tested whether empagliflozin (Jardiance), a diabetes drug, can help the heart recover after aortic valve replacement. 206 patients took either the drug or a placebo for six months. The goal was to see if the drug reduces heart muscle thickness and improves symptoms.

This study looked at whether a 16-week strength training program can prevent or reduce late effects like muscle loss, heart disease, and diabetes in adults who had a bone marrow transplant as children. 28 survivors and a matched control group participated. The goal was to see if …

This study looked at 742 people newly diagnosed with wet age-related macular degeneration (nAMD) who received 3 monthly injections of faricimab (Vabysmo) instead of the usual 4. The goal was to see how long the effect lasted before another injection was needed. Researchers tracke…

This study tested whether a hydrochloric acid lock can help treat central line infections in 212 cancer and blood disease patients. The acid solution was placed in the line for 10 minutes, repeated three times, alongside standard antibiotics. The goal was to see if it reduces tre…

This study compared a newer pacing method, called HIS or left bundle branch (LBB) pacing, to the standard biventricular pacing in 150 heart failure patients with a specific heart electrical problem (left bundle branch block). The goal was to see if the new method could improve he…

This study tested whether a shallow (2 cm) or deeper (4 cm) nasal swab is better at detecting COVID-19 using rapid antigen tests. Over 300 adults in Denmark each received both swab depths, and results were compared to a standard throat PCR test. The goal was to find the best bala…

This study looked at whether a saliva test can accurately measure cortisol levels after a dexamethasone suppression test, compared to the standard blood test. Researchers studied about 100 patients with adrenal incidentalomas (non-cancerous growths on the adrenal gland) and 100 h…

This study tested whether a 4-month gym exercise program helps young adults (18-35) taking antipsychotic medication for psychosis or mood disorders feel better in their daily lives. 226 participants were randomly assigned to either continue their usual care or add gym workouts. R…

This study tested two online self-management programs for 163 adults with chronic non-cancer pain who were on a waiting list for specialist care. One program was a series of educational videos about pain, and the other was an online session teaching skills to manage pain. The goa…

This study tested whether a supervised resistance training program could help lymphoma patients maintain muscle mass and physical function while undergoing chemotherapy. Forty-two adults with newly diagnosed lymphoma were randomly assigned to either the exercise program or usual …

This study tested a non-invasive device that stimulates the vagus nerve through the ear to see if it can reduce fatigue in people with lupus. 75 participants received either active or sham stimulation over two phases. The main goal was to measure changes in fatigue using a standa…

This study looked at 58 patients scheduled for pancreatic surgery due to suspected cancer. Researchers collected blood samples before and after surgery to measure immune function and inflammation. They then tracked complications like low blood pressure and infections. The goal wa…

This study followed 268 adults with end-stage kidney disease on dialysis. Each participant wore a Holter heart monitor for 7 days to track irregular heartbeats. Researchers then looked for links between those heart patterns and serious outcomes like sudden cardiac death, heart at…

This study looked at the experiences of 126 people in Denmark who rely on a breathing machine at home, along with their families and the trained caregivers who help them. The goal was to understand the challenges and successes of this life-sustaining care. No new treatments were …

This study developed and tested a program to help nurses better support relatives of patients with acquired brain injury or malignant brain tumors. The program included nurse training, a dialog tool, a peer support list, videos, and documentation guidelines. Researchers tested it…

This study tested a new ultrasound technique to see the smallest blood vessels in lymph nodes on the neck. Researchers wanted to know if this method could tell the difference between healthy and cancerous lymph nodes. Twenty adults with head and neck cancer, lymphoma, or healthy …

This study looked at 165 trauma patients to see how often they had low blood oxygen (hypoxemia) during their first 24 hours in the hospital. Researchers used a special finger clip to track oxygen levels and compared daytime vs. nighttime episodes. The goal was to understand when …

This study looked at 86 people with severe aortic valve stenosis who had valve replacement surgery. Researchers used special MRI scans to measure scarring in the heart muscle before and one year after surgery. The goal was to see if the scarring improves and whether MRI could hel…

This study looked at how blood sugar levels relate to sugar levels in the brain of 14 seriously ill patients with acute brain injury. Researchers used special monitoring tools to measure brain sugar and oxygen. The goal was to better understand this relationship and create a math…

This study tested a seven-session pain school program for 82 adults with chronic non-cancer pain. The program included teaching, group discussions, and exercises led by a team of pain specialists. The goal was to see if patients found the program helpful and relevant to their nee…

This study tracked 51 lung cancer patients before and after video-assisted thoracoscopic surgery to see how much time they spent lying down, sitting, or standing. Researchers also looked at what prevented patients from moving more. The goal was to understand barriers to early mob…

This study tested whether a non-invasive device that uses electrical signals to estimate stroke volume (the amount of blood the heart pumps with each beat) gives consistent results on different days. Twelve healthy volunteers (6 men, 6 women) had their heart function measured at …

This study looked at over 1,200 people in Denmark who had a stem cell transplant for blood diseases, some as far back as 1970. Researchers used detailed surveys to measure late effects and quality of life. The goal is to find out what medical and personal factors help survivors f…

This study tested whether doctors can more accurately find the cricothyroid membrane (a critical spot for emergency airway access) on a neck model with a twisted windpipe using either their fingers or an ultrasound device. 61 anesthesiologists participated, each using one of the …

This completed study looked at whether people with COPD have abnormal leakage in their lung capillaries during exercise, which could contribute to shortness of breath. Researchers compared 32 participants (COPD patients and healthy controls) by measuring lung permeability before …

This study looked at how removing parts of the small intestine affects gut hormone levels after eating. Researchers measured these hormones in 39 people with different types of bowel resection and compared them to healthy controls. The goal was to better understand digestion and …

This completed study looked at 209 patients with bacterial endocarditis, a serious heart valve infection, to understand how common anemia is and what causes it. Researchers measured blood markers for inflammation and anemia from diagnosis up to 6 months after hospital discharge. …

This study tested whether it is safe to get patients with severe brain injuries out of bed early in the intensive care unit. 22 patients were moved using a special device called the Sara Combilizer, and researchers measured brain oxygen levels and other vital signs. The goal was …

This study looked at how a 12-week program of high-intensity interval training (HIIT) affects fitness and fatigue in 55 people with lupus. Researchers wanted to understand if certain immune system signals (interferons) change how the body adapts to exercise. Participants were ran…