Rigshospitalet, Denmark

This study will compare a newer, less invasive heart procedure called hybrid revascularization to standard coronary artery bypass grafting (CABG) in over 1,000 people with multiple blocked heart arteries. The hybrid approach combines a small incision to graft a key artery with st…

This study tests whether staying alcohol-free for six months after a heart ablation procedure can reduce the return of atrial fibrillation (AF), a common heart rhythm problem. Researchers will enroll 414 adults who drink at least three alcoholic beverages per week and are schedul…

This study compares a newer pacing method (HIS or left bundle branch pacing) to the standard biventricular pacing in 1100 heart failure patients across Nordic countries. The goal is to see if the new approach reduces death or unplanned heart failure hospitalizations. Participants…

This study will compare different pulse field ablation systems used to treat atrial fibrillation (AF), a common heart rhythm problem. Over 1,100 patients will receive one of the standard treatments depending on the time period they are treated. Researchers will track whether AF r…

This study will test whether giving an extra antibiotic during a heart valve replacement procedure (TAVI) can lower the chance of bloodstream infection or death within 6 months. About 2,000 patients in Denmark will take part. Half will get the standard antibiotic, and half will g…

This study tests two different ways to program an implantable defibrillator (ICD) to stop dangerous fast heartbeats. About 4,000 people with heart disease who need an ICD will be assigned to one of two pacing patterns (burst or ramp) and followed for up to 10 years. The goal is t…

This study tests a special imaging scan (Tc-GSA SPECT/CT) to see if it can predict liver failure after surgery for liver tumors. About 192 adults in Denmark will receive the scan before their operation. The goal is to compare this new method with standard tests and find the best …

This study tests a new, non-invasive MRI method to measure oxygen levels in the portal vein, which carries blood from the gut to the liver. Researchers will compare 20 people with meal-related abdominal pain due to narrowed gut arteries (chronic mesenteric ischemia) to 20 people …

This study tests a stepped-care model to support relatives of people with acquired brain injury or malignant brain tumor. The model offers basic support to all, with extra help for those who need it, based on screening. Researchers will measure changes in caregiver burden and wel…

This study looks at whether structured physical activity and play can help preschool children with cancer improve their motor skills and development. About 82 children aged 1-5 will take part in a 9-month program that includes group play at the hospital, parent education, and onl…

This study tests a new early rehabilitation program for people who have had lumbar spinal fusion surgery for low back pain. The program combines conversation-based education with graded physical activity, starting two weeks after surgery. Researchers will include 12 participants …

This study looks at whether stopping combined birth control pills changes a key brain chemical called serotonin, which affects mood and memory. Sixty healthy women aged 18-39 who currently take a specific type of pill will either stop or continue their pill for up to a year. Rese…

This observational study will follow 100 children in Denmark who receive a stem cell transplant for blood cancer or other serious blood disorders. Researchers will test their thinking skills, physical abilities, and daily activity before the transplant and for one year after. The…

This study looks at how doctors trust artificial intelligence (AI) when it estimates a baby's weight during pregnancy. Over 300 clinicians will review ultrasound cases and choose between AI-based or traditional weight estimates. Some doctors will also see how reliable the AI is. …

This study will implant a small heart monitor under the skin of 100 people with moderate-to-severe mitral valve regurgitation who have few or no symptoms. The device will track heart rhythms for up to three years to find hidden atrial fibrillation that standard tests might miss. …

This study looks back at the medical records of 50 adult ICU patients with COVID-19 who needed a life-support machine called ECMO. The goal is to understand how often bleeding and dangerous blood clots happen, and how blood transfusions and blood thinners affect their care. The f…

This study looks at how receiving parenteral nutrition (IV feeding) changes the results of a liver stiffness test called FibroScan in people with short bowel syndrome. Researchers will measure liver stiffness before, during, and after the infusion in 20 stable adult patients. The…

This study will follow 200 adults undergoing surgery for liver, esophagus, or pancreatic cancer. Researchers want to see how patients' expectations before surgery relate to their pain, painkiller use, and recovery afterward. The goal is to learn how to better manage pain and impr…

This study will follow 175 children and young adults who had a bone marrow transplant before age 18. Researchers will test their thinking, memory, and attention skills, and check for links to physical health issues like metabolism and fitness. The goal is to find early warning si…