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Acid lock may beat blood infections in cancer patients

NCT ID NCT05376566

Completed Disease control Sponsor: Rigshospitalet, Denmark Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 01, 2026 · Updated 31 times

Summary

This study tested whether a hydrochloric acid lock placed in central lines could reduce treatment failure for bloodstream infections in 212 cancer and blood disease patients. Participants received either the acid lock or a saltwater placebo alongside standard antibiotics. The goal was to see if the acid lock lowers the chance of persistent infection, relapse, or line removal.

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Contacts and locations

Locations

  • Department of Haematology, Copenhagen University Hospital

    Copenhagen, 2100, Denmark

  • Department of Paediatrics and Adolescent Medicine, Aarhus University Hospital

    Aarhus, 3200, Denmark

  • Department of Paediatrics and Adolescent Medicine, Copenhagen University Hospital

    Copenhagen, 2100, Denmark

  • Department of Paediatrics and Adolescent Medicine, Odense University Hospital

    Odense, 4000, Denmark

Conditions

Explore the condition pages connected to this study.

CENTRAL LINE-ASSOCIATED BLOODSTREAM INFECTION (CLABSI) CENTRAL LINE-ASSOCIATED BLOODSTREAM INFECTION (CLABSI)