Poznan University Of Medical Sciences

This study compares three versions of a nerve block (PENG block) for people aged 65 and older having hip surgery. All participants receive the same base painkiller, but some get extra medications (dexamethasone and/or dexmedetomidine) either through an IV or near the nerves. The …

This study compares three versions of a pain-blocking injection (PENG block) in 120 adults aged 65 and older having hip surgery. One group gets the standard block, while two others get an added medication (dexamethasone or dexmedetomidine) to see if pain relief lasts longer. The …

This study looks at whether adding a small dose of dexmedetomidine to a standard nerve block (PENG block) can provide longer-lasting pain relief after hip surgery in adults aged 65 and older. Participants will be randomly assigned to receive either the standard block or the block…

This study compares two types of nerve blocks to control pain after total knee replacement. 80 adults aged 65 and older will receive one of two combinations of numbing injections. The goal is to see which method provides longer pain relief and helps people get moving sooner after…

This study looks at 120 children aged 3 to 12 having foot or ankle surgery. All get a standard nerve block, plus one of three extra medications: dexamethasone, dexmedetomidine, or both. The goal is to see which combination provides the longest pain relief and reduces the need for…

This study tests two types of nerve blocks to see which one better controls pain after hip replacement surgery. 90 adults aged 65 and older will be randomly assigned to receive one of the two blocks. The goal is to reduce the need for strong painkillers and help patients recover …

This study looks at whether adding dexamethasone or dexmedetomidine to a standard numbing medicine can improve pain control and reduce the need for strong painkillers after total knee replacement. About 96 older adults having knee surgery will be randomly assigned to one of three…

This study compares three different nerve block techniques to see which provides the best pain relief after hip replacement surgery while allowing patients to move their legs sooner. About 93 adults aged 65 and older having elective hip replacement will be randomly assigned to on…

This study looks at whether giving the anti-inflammatory drug dexamethasone through a vein or near the nerves works better for controlling pain after arm or hand surgery in children. Ninety kids weighing more than 5 kilograms will take part. The goal is to find the best method to…

This study compares two medications, dexamethasone and dexmedetomidine, when added to a standard nerve block for pain after lower back surgery. The goal is to see which one reduces the need for strong painkillers (opioids) more effectively. 150 adults scheduled for elective lumba…

This study tests whether measuring drug levels in the blood can help doctors personalize antidepressant doses for people aged 12 and older with major depression. Participants will receive one of three common antidepressants (fluoxetine, sertraline, or escitalopram), and doses wil…

This study looks at whether injecting dexamethasone into a nerve block or giving it through an IV works better for pain and swelling after total knee replacement. About 90 adults over age 65 having knee surgery will be randomly assigned to one of the two methods. Researchers will…

This study follows 1,500 twins aged 15 to 44 over five years to learn how metabolic syndrome and related conditions like fatty liver disease, heart problems, and diabetes start and progress. Researchers will track changes in the liver and other organs, and look at how genes, envi…

This study tests whether using a breath measurement called respiratory quotient (RQ) can help doctors give the right amount of calories to ICU patients on breathing machines. About 200 adults will be randomly assigned to standard nutrition care or care that also adjusts food type…

This study tests a special software that predicts low blood pressure during major aortic surgery. Researchers will compare it to standard monitoring in 200 adults having planned aortic surgery. The goal is to see if the software helps doctors keep blood pressure stable, potential…