New nerve block combo could reduce hip surgery pain in seniors

NCT ID NCT07449442

Recruiting now Symptom relief Sponsor: Poznan University of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether combining two nerve blocks (iPACK and adductor canal block) with a numbing drug called ropivacaine can reduce pain and inflammation after total hip replacement. Sixty older adults (65-100 years) having hip surgery will be randomly assigned to receive either the active nerve blocks or a placebo (salt water). The main goal is to see if the blocks lower a blood marker of inflammation called the Systemic Inflammation Response Index (SIRI).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ropivacaine (a numbing medication)
What this could lead to: If it works, this could lead to a standard way to reduce pain and inflammation after hip replacement, helping older patients recover more comfortably.
What could go wrong: This is a small, early-stage trial (60 people) testing a well-known drug in a new combination. The results may not apply to all patients, and the nerve blocks carry rare risks like infection or nerve damage.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS

Contacts and locations

Locations

Poznan University of Medical Sciences
RECRUITING

Poznan, 62-701, Poland

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