New nerve block combo could reduce hip surgery pain in seniors

NCT ID NCT07449442

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether combining two nerve blocks (iPACK and adductor canal block) with a numbing drug called ropivacaine can reduce pain and inflammation after total hip replacement. Sixty older adults (65-100 years) having hip surgery will be randomly assigned to receive either the active nerve blocks or a placebo (salt water). The main goal is to see if the blocks lower a blood marker of inflammation called the Systemic Inflammation Response Index (SIRI).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ropivacaine (a numbing medication)

What this could lead to

If it works, this could lead to a standard way to reduce pain and inflammation after hip replacement, helping older patients recover more comfortably.

What could go wrong

This is a small, early-stage trial (60 people) testing a well-known drug in a new combination. The results may not apply to all patients, and the nerve blocks carry rare risks like infection or nerve damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for KNEE OSTEOARTHRITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Poznan University of Medical Sciences

    RECRUITING

    Poznan, 62-701, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••