Which drug makes spine surgery recovery less painful? new trial aims to find out.

NCT ID NCT07180940

Recruiting now Symptom relief Sponsor: Poznan University of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether adding dexamethasone or dexmedetomidine to a standard nerve block (with ropivacaine) can better control pain after lower back surgery. 150 adults scheduled for elective lumbar spine surgery will be randomly assigned to one of three groups. The main goal is to see which combination reduces the need for opioid painkillers in the first 24 to 48 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexamethasone or dexmedetomidine added to ropivacaine
What this could lead to: If it works, this could point toward a better way to manage pain after spine surgery, reducing the need for strong opioids.
What could go wrong: This is a small, early-phase trial focused on short-term pain relief. Results may not apply to all spine surgeries or patients, and both drugs have known side effects like nausea or drowsiness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

vertebral column disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SPINAL DISEASES SPINE DISEASE

Contacts and locations

Locations

Poznan University of Medical Sciences
RECRUITING

Poznan, 62-701, Poland

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