Oregon Health And Science University

This study tested a new closed-loop system that automatically delivers both insulin and pramlintide to manage blood sugar in 33 adults with type 1 diabetes. Pramlintide slows digestion to prevent blood sugar spikes after meals. The system was compared to insulin alone. Researcher…

This study tested a new fully-closed insulin delivery system that automatically adjusts insulin based on activity and missed meals, compared to a standard hybrid system. 29 adults with type 1 diabetes used both systems to see which kept blood sugar in a healthy range more often. …

This study looked at how people with PKAN, a rare genetic brain disorder, respond to a special vitamin metabolite. Researchers wanted to see if it is safe and if it changes any signs of the disease. 77 people aged 3 months to 89 years took part.

This study tested a personalized surgical approach for children with obstructive sleep apnea who have small tonsils or Down syndrome. Instead of the standard tonsil and adenoid removal, doctors used a sleep endoscopy to see exactly where the airway collapses and chose surgeries b…

This study tested whether having a community health nurse deliver birth control to women at home could reduce unwanted pregnancies. It involved 103 low-income and minority women who were not pregnant but wanted to delay pregnancy. The nurses provided oral contraceptives or Depo-P…

This study tested whether a procedure called ERCP with sphincterotomy can lower the risk of repeat pancreatitis attacks in people with pancreas divisum, a condition where the pancreas ducts don't join normally. 181 adults who had at least two pancreatitis episodes were randomly a…

This pilot study tested whether giving two asthma medications (ipratropium and dexamethasone) to children during ambulance transport can reduce hospital admissions. The study included 44 children aged 2 to 17 with severe wheezing. The goal was to see if this early treatment is fe…

This study tested a video-based program called Tele-STELLA for family members caring for someone with moderate to late-stage Alzheimer's or related dementia. The program connects caregivers with a guide to find ways to manage upsetting behaviors. The goal was to see if it could r…

This study tested a video-based program called STELLA-FTD to help family caregivers of people with frontotemporal dementia (FTD). Sixteen caregivers participated in the program, which aimed to reduce their stress and improve their quality of life. The approach used videoconferenc…

This study tested a program called SHARP-CG for older Black caregivers of people with dementia. Caregivers, their loved ones with dementia, and a support person walked together while using a tablet to look at old neighborhood photos and talk about memories. The goal was to see if…

This completed pilot study tested a digital mental health platform called Center M for pregnant women with or at risk for perinatal depression. 116 participants were randomly assigned to either use the Center M app with telehealth mindfulness sessions and digital home practice, o…

This study tested whether a procedure called pancreatic endotherapy can reduce pain in people with chronic pancreatitis whose main pancreatic duct is blocked by stones or narrowings. Fourteen adults with severe daily pain were randomly assigned to get either an ultrasound alone o…

This study looked at how sleep, body clocks, and daily habits affect nighttime blood pressure in Black adults. Researchers monitored 30 participants in a lab for a week to measure blood pressure changes. The goal is to find better ways to treat high blood pressure by targeting sl…

This study tested whether women could safely remove their own intrauterine devices (IUDs) using simple techniques. Thirty women who were already scheduled for IUD removal at a clinic tried the methods. The goal was to see how often self-removal worked and to learn what women thin…

This study tested two special ultrasound techniques—shear wave elastography and microvascular flow imaging—to see how leg muscle injuries change during recovery. Nine people with lower extremity injuries were scanned multiple times as they healed. The goal was to see if these sca…

This study looked at how a pill form of THC (dronabinol) affects sleep and thinking in 18 adults. Some participants used cannabis frequently (more than 3 times a week), while others rarely used it (less than 10 times ever). Researchers measured sleep stages, alertness, memory, an…

This study looked at 94 adults with a recent spinal cord injury to see if keeping their blood pressure at a higher or lower target helped them heal better. Participants were split into two groups: one with a standard blood pressure goal and one with a higher goal, maintained for …

This pilot study tested whether giving metformin around the time of hip or knee replacement surgery is practical and helps control blood sugar. Forty adults took either metformin or a placebo for two weeks before surgery and a few days after. The main goal was to see if a larger …

This study looked at whether 8 weeks of yogic breathing practices can improve the flow of cerebrospinal fluid (CSF) around the brain and spine. Twenty-six healthy adults were split into two groups, each doing different breathing exercises. Researchers measured CSF flow using MRI …