Oregon Health And Science University

This study compared two surgical approaches for treating obstructive sleep apnea (OSA) in children. It involved 30 children, aged 2-18, who had moderate OSA along with either small tonsils or Down syndrome. Researchers tested if a personalized surgery, guided by a special sleep s…

This small pilot study tested whether giving the diabetes medication metformin around the time of hip or knee replacement surgery is practical for a larger future trial. It involved 40 patients, some with diabetes and some without, to see if they could be recruited easily and tak…

This study tested a new automated insulin delivery system (artificial pancreas) that can detect when someone with type 1 diabetes eats a meal but forgets to tell their insulin pump. The system then automatically gives the needed insulin. Researchers compared this new system again…

This study tested whether a minor endoscopic procedure could reduce the risk of future painful pancreatitis attacks in adults with a specific pancreas anatomy called pancreas divisum. 181 participants who had experienced at least two prior attacks were randomly assigned to receiv…

This study tested whether keeping a patient's blood pressure at a higher target range in the first week after a spinal cord injury leads to better recovery. Researchers compared two different blood pressure targets to see which one improved patients' movement, sensation, pain, an…

This study tested whether a vitamin metabolite could help control Pantothenate Kinase-Associated Neurodegeneration (PKAN), a rare genetic brain disorder. Researchers enrolled 77 people with PKAN across North America to check if the treatment was safe and if it affected disease ma…

This study tested if adding a second drug, pramlintide, to an automated insulin delivery system could better control blood sugar after meals for people with type 1 diabetes. Thirty-three adults tried the system using insulin alone on one clinic day and insulin plus pramlintide on…

This study tested whether a specialized endoscopic procedure could reduce pain in people with chronic pancreatitis who have blocked pancreatic ducts. Fourteen adults with significant daily pain participated in this pilot trial, where some received the actual treatment while other…

This study tested a program called SHARP-CG, designed to support older Black caregivers of people with dementia. Small groups walked together three times a week for 16 weeks, using a tablet to view historical photos of their neighborhood as conversation starters. Researchers meas…

This study tested a program called Tele-STELLA, which uses video calls to support family members caring for a loved one with moderate to severe dementia. Over 375 caregivers worked with trained guides from their own homes to learn strategies for managing difficult behaviors like …

This study tested a program called STELLA-FTD, which uses video calls to connect family caregivers with trained guides. The goal was to teach caregivers strategies to manage difficult behaviors in their loved ones with frontotemporal dementia and to reduce their own stress and bu…

This study tested a new digital therapy program called Center M, designed to help women manage depression during and after pregnancy. It compared a shorter, online mindfulness course with app-based homework to standard care. The goal was to see if this more convenient digital app…

This study aimed to see if practicing specific yoga breathing exercises for 8 weeks could change how fluid flows around the brain and spine. Researchers enrolled 26 healthy adults who did not regularly practice yoga or meditation. They used MRI scans before and after the breathin…

This small, early-stage study aimed to understand how a pill containing THC (the main active ingredient in cannabis) affects sleep. Researchers tested 18 healthy young adults, including both regular cannabis users and non-users, to see how different doses influenced their sleep p…