Can a common diabetes drug help after joint surgery? small study aims to find out
NCT ID NCT06280274
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tested whether giving metformin around the time of hip or knee replacement surgery is practical and helps control blood sugar. Forty adults took either metformin or a placebo for two weeks before surgery and a few days after. The main goal was to see if a larger trial is possible, not to prove metformin works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Metformin
What this could lead to
If this pilot shows it's feasible, it could lead to a larger trial testing whether metformin helps control blood sugar after joint replacement surgery.
What could go wrong
This is a small pilot study with only 40 people, so results may not apply broadly. It focuses on feasibility, not on proving metformin works for blood sugar control.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Oregon Health & Science University
Portland, Oregon, 97239, United States