Oregon Health And Science University

This study tests a drug called clofazimine for people with a chronic lung infection caused by Mycobacterium avium complex (MAC). The goal is to see if adding clofazimine to standard treatment can clear the bacteria from sputum and improve walking ability and fatigue. About 102 ad…

This study tests whether using a chlorhexidine rinse after bowel movements can lower the rate of urinary tract infections (UTIs) in post-menopausal women who already use vaginal estrogen and have frequent UTIs. About 136 women aged 55–89 will be randomly assigned to use either th…

This study tests whether giving people who use methamphetamine rewards for reaching their own harm-reduction goals (like using less or seeking help) can lower overdose rates and increase engagement with treatment and support services. Over 1,200 adults who recently used stimulant…

This study tests a smartphone app called COACH that helps patients and doctors work together to manage high blood pressure. About 550 adults with high blood pressure will use the app to track their home readings and share them with their care team. The goal is to see if the app h…

This study tests a program designed to help new bus operators avoid weight gain and adjust to their jobs. About 284 new hires from several transit authorities will take part for two years. Some will receive the special program, while others will follow usual work practices. The g…

This study looks at two ways to repair a small gap in the back of the voice box (laryngeal cleft) that causes swallowing problems in children. One method injects a gel to build up the area, the other uses stitches. About 128 children aged 1 to 10 will be randomly assigned to one …

This study looks at whether virtual group support from peers who have had vaginoplasty can help transgender and non-binary people feel more prepared and less stressed before surgery. Researchers will compare this support to standard care with extra educational materials. The goal…

This study tests a special exercise program called TURN-IT designed to improve how people with Parkinson's disease turn, which is a common cause of falls. About 55 participants with Parkinson's and a history of falls will either do the 6-week program or continue as usual. The goa…

This study tests a program called COMPASS-NP for home care workers who have chronic pain. The program combines pain education, coping strategies, and safety tips to help workers feel better and stay active at work and in life. About 140 adults who work as home care workers and ha…

This study looks at how the body's internal clock affects heart disease risk, especially in people with obesity. Researchers will compare 16 lean and obese adults to see if heart risk markers change throughout the day. The goal is to understand why obesity may increase heart prob…

This study checks if simple sleep questionnaires can accurately detect obstructive sleep apnea in children with Down syndrome, who are at higher risk. About 81 children aged 2-17 will answer sleep questions and have their results compared to a standard overnight sleep test. The g…

This study looks at how well COVID-19 booster vaccines work in people with rheumatic diseases (like arthritis) who take medications that affect their immune system. About 129 participants will receive a COVID-19 booster alone, with another vaccine (like Tdap or hepatitis A), or a…

This study looks at whether a special type of eye scan (functional OCT) can detect early blood vessel damage in people with diabetic retinopathy without needing a dye injection. Researchers will compare the new scan to the standard dye-based test in 165 adults with diabetes. The …

This study tests a new type of eye scan (OCTA) that doesn't require dye injections to see blood vessels in the back of the eye. Researchers want to see if it can measure damage from diabetic retinopathy as well as or better than current methods. About 290 people with diabetes wil…

This study was designed to see how well compounds from a standardized ashwagandha supplement are absorbed in healthy adults aged 65 and older. Researchers planned to measure levels of active ingredients in the blood after taking the supplement. The study was withdrawn before any …