Hope for Hard-to-Treat lung infection: old drug shows promise

NCT ID NCT02968212

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called clofazimine for people with a chronic lung infection caused by Mycobacterium avium complex (MAC). The goal is to see if adding clofazimine to standard treatment helps clear the bacteria from sputum and improves walking ability and fatigue. About 102 adults with confirmed MAC lung disease are taking part. The drug is not a cure, but aims to better control the infection.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Louisiana State University

    Baton Rouge, Louisiana, 70803, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of South Florida

    Tampa, Florida, 33620, United States

  • University of Texas Health Science Center

    Tyler, Texas, 75708, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.