Oregon Health And Science University

This phase 2 trial will test two drugs, finerenone and sotagliflozin, in 57 people with type 1 diabetes who are at risk for heart and kidney problems. The goal is to see if matching the right drug to each person's specific diabetes subtype can improve early signs of heart and kid…

This study tests whether offering gift cards can help people leaving jail stick with their medication for opioid use disorder. Participants earn up to $600 for attending appointments and counseling over three months after release. The goal is to reduce the high risk of overdose d…

This pilot study will test whether the antibiotic cefotetan works as well as standard treatments for E. coli infections in the blood or urinary tract. About 84 hospitalized adults will be randomly assigned to receive cefotetan or usual care. The goal is to see if cefotetan can su…

This study looks at how Rocklatan eye drops change blood flow in the eyes of 30 people with early-stage glaucoma. Researchers will use special imaging to measure blood flow before and after using the drops for up to a year. The goal is to better understand the drug's effects on e…

This study tests a smartphone app called DailyDose that gives personalized advice on insulin doses and carbohydrate intake for people with type 1 diabetes who use multiple daily injections. The app uses data from continuous glucose monitors and insulin pens. Researchers want to s…

This study tests two progestin-only birth control pills—drospirenone and norethindrone—to see which one helps control high blood pressure after a pregnancy complicated by preeclampsia. Fifty women will take one of the pills daily for six weeks after leaving the hospital. The goal…

This phase III trial tests a procedure called FETO for severe congenital diaphragmatic hernia (CDH), where the diaphragm is incomplete and organs move into the chest. Doctors place a temporary balloon in the baby's windpipe before birth to help the lungs grow. The study will comp…

This study tests whether a leadership training program can help National Guard leaders better support their team's mental health. About 5,400 Guard members, leaders, and their spouses will take part. The training includes a one-hour online course, a behavior tracking exercise, an…

This study tests a decision-making tool that helps healthcare providers give brief behavioral counseling to parents of children aged 18-65 months with common behavior concerns. About 60 parents will receive guidance during a regular medical or behavioral health visit. The goal is…

This study tests whether a training program for therapists can help them use powered mobility devices with young children (ages 12-32 months) who have severe cerebral palsy. Therapists will learn how to use the devices during everyday routines at home or in early childhood settin…

This study tests a program called Center M, which offers weekly one-hour online group sessions led by a trained therapist. The goal is to see if it helps reduce symptoms of depression in pregnant people compared to standard care. About 160 participants will join, and their depres…

This early-stage study will test whether a single dose of psilocybin (25 mg) combined with therapy sessions is safe and feasible for women aged 18-45 with chronic pelvic pain that hasn't improved with standard treatments. The study involves 15 participants and focuses on recruitm…

This study tests two programs designed to help low-income parents prepare their 3- to 4-year-old children for kindergarten. One program gives parents a simple checklist; the other pairs families with a community health worker for personalized coaching. Researchers will measure ch…

This study aims to help grandparents who are raising their grandchildren full-time improve their heart health. Researchers will test a program that teaches healthy eating and physical activity. About 70 grandparents in Oregon will take part, and the study will check if the progra…

This study aims to improve balance problems after a mild traumatic brain injury (concussion). Researchers will develop a new exercise program that focuses on how the body responds to imbalance, and compare it to standard balance therapy. The study will involve 80 adults aged 18-6…

This study explores whether virtual reality (VR) construction tasks can detect changes in performance caused by lack of sleep. Researchers will enroll 12 participants and have them perform VR tasks after different sleep conditions. The goal is to see if VR can reliably measure sl…

This study will give 50 women who had gestational diabetes a continuous glucose monitor (Stelo) to wear after giving birth. The goal is to learn how their blood sugar levels change during daily life and how well the device works. Participants will use the monitor for up to 6 week…

This study will give 40 pregnant people a Garmin activity tracker to see if it's a useful tool for measuring and encouraging physical activity during pregnancy. Researchers want to learn how often people wear the device and if they find it helpful. The goal is to gather informati…

This study will test if simple, bedside heart tests (ultrasound, EKG, and blood tests) can accurately detect heart problems in pregnant women who regularly use methamphetamine. Researchers will compare these quick tests to a full heart ultrasound. The goal is to find a faster, ea…