Nuvasive
Clinical trials sponsored by Nuvasive, explained in plain language.
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Stem cell graft shows promise for back pain relief in spinal fusion
Disease control CompletedThis study looked at whether a special bone graft called Osteocel Plus, which contains stem cells, helps bones in the spine fuse together after surgery. It involved 51 adults with degenerative disc disease who had not improved with other treatments. The goal was to see if this gr…
Sponsor: NuVasive • Aim: Disease control
Last updated May 17, 2026 08:53 UTC
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New minimally invasive back surgery shows promise in early study
Disease control CompletedThis study looked at two surgical techniques for treating painful degenerative disc disease in the lower back. Researchers compared a newer, less invasive method called MAS PLIF with the standard open surgery. They tracked complications and pain levels in 67 adults who had one or…
Sponsor: NuVasive • Aim: Disease control
Last updated May 17, 2026 08:52 UTC
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New spine plate shows promise in fusion surgery study
Disease control CompletedThis study tested a new metal plate system used during spine surgery to help bones fuse together. It included 75 adults with conditions like degenerative disc disease or scoliosis. The main goals were to see how safe the plate is and how well it helps the spine bones heal togethe…
Sponsor: NuVasive • Aim: Disease control
Last updated May 17, 2026 08:52 UTC
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New bone putty may replace painful hip graft in spine surgery
Disease control CompletedThis study tested whether a man-made bone graft material (AttraX Putty) works as well as using the patient's own bone (autograft) for spinal fusion surgery. 45 adults with degenerative spine conditions were enrolled. The goal was to see if the putty could help bones fuse together…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated May 17, 2026 08:46 UTC
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Stem cell bone graft shows promise for back pain relief
Disease control CompletedThis study tested a special bone graft material called Osteocel Plus in 28 adults with degenerative disc disease who needed spinal fusion surgery. The material contains stem cells to help bones heal together. The goal was to see if it works as well as using the patient's own bone…
Sponsor: NuVasive • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New artificial disc offers hope for chronic neck pain sufferers
Disease control CompletedThis study tested a new artificial disc (Simplify® Disc) for people with two damaged discs in the neck causing arm pain, numbness, or weakness. The goal was to see if the disc is as safe and effective as standard fusion surgery. 182 participants received the disc or fusion, and s…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New artificial disc takes on standard neck fusion in major trial
Disease control CompletedThis study tested a new artificial disc (NeoDisc) against standard neck fusion surgery in 488 adults with a single damaged disc in the neck. The goal was to see if the new disc is as safe and effective at reducing neck disability, avoiding repeat surgery, and keeping nerves healt…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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3D-Printed spine implant shows promise in small trial
Disease control CompletedThis study tested a new 3D-printed titanium implant for spine fusion surgery in 36 adults with degenerative disc disease, spondylolisthesis, or scoliosis. The implant was used to stabilize the spine and help bones fuse together. Researchers measured safety, fusion rates, and pati…
Sponsor: NuVasive • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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5-Year data shows disc implant holds up well
Disease control CompletedThis study followed 145 people who received the Simplify Cervical Artificial Disc to replace a damaged disc in the neck. Researchers checked if the implant was still working safely and effectively after 5 years. The goal was to see if patients had less neck pain and avoided furth…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New bone graft material shows promise in spine surgery study
Disease control CompletedThis study tested a bone graft material called Osteocel Plus in people with degenerative disc disease and back pain who needed spine fusion surgery. 104 adults received the graft during a minimally invasive procedure called XLIF. Researchers tracked how well the bones fused over …
Sponsor: NuVasive • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Stem cell bone graft shows promise for back pain relief
Disease control CompletedThis study tested a special bone graft called Osteocel Plus, which contains stem cells, in 19 people with degenerative disc disease who needed spinal fusion surgery. The goal was to see if it helps bones fuse together as well as the standard bone graft taken from the patient's ow…
Sponsor: NuVasive • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New spinal implant shows promise for chronic back pain
Disease control CompletedThis study tested a new spinal implant (Modulus ALIF) in 123 adults with back problems like degenerative disc disease or spinal stenosis. The goal was to see if the device is safe and helps fuse the spine bones together. Researchers checked for complications, bone healing on X-ra…
Sponsor: NuVasive • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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Back surgery showdown: which fix works best?
Disease control CompletedThis study compared two types of spine surgery (XLIF and TLIF) in 55 adults with a slipped vertebra causing leg pain or trouble walking. The goal was to see which procedure led to better function and less pain over two years. Both surgeries aim to stabilize the spine and relieve …
Sponsor: NuVasive • Aim: Disease control
Last updated May 12, 2026 13:39 UTC
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New artificial disc matches standard surgery for neck pain relief
Disease control CompletedThis study tested a new artificial disc, called Simplify®, for people with cervical degenerative disc disease causing arm pain or nerve problems. 150 adults received either the new disc or standard fusion surgery. The goal was to see if the new disc was as safe and effective at r…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated May 07, 2026 18:38 UTC
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New back surgery shows promise for disc pain relief
Disease control CompletedThis study tested a new type of spine surgery called ILIF™ in 77 adults with degenerative disc disease (a worn-out disc in the lower back). The surgery involved removing pressure on nerves and fusing the bones together with a small plate and bone graft. Researchers measured chang…
Sponsor: NuVasive • Aim: Disease control
Last updated May 05, 2026 11:53 UTC
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Artificial disc holds up over 5 years for neck pain sufferers
Disease control CompletedThis study checked how safe and effective the Simplify® Cervical Artificial Disc is over 5 years in 291 people with cervical degenerative disc disorder. The disc is designed to replace a damaged disc in the neck to relieve pain and maintain movement. The study measured success by…
Sponsor: NuVasive • Aim: Disease control
Last updated May 04, 2026 16:19 UTC
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New spine implants show promise for chronic back pain sufferers
Disease control CompletedThis study looked at the safety and performance of two types of spine implants (MLX and XLX ACR) in 109 adults with degenerative back problems like disc disease, slipped vertebrae, or scoliosis. The goal was to see how well the implants worked and if they caused any complications…
Sponsor: NuVasive • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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New bone graft shows promise in neck fusion surgery
Disease control CompletedThis study looked at a bone graft material called Osteocel Plus used during neck fusion surgery (ACDF) in 182 people with degenerative disc disease. The goal was to see how well the bones fused together and how safe the material was over 24 months. Results were compared to older …
Sponsor: NuVasive • Aim: Disease control
Last updated Apr 29, 2026 15:05 UTC
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Can a simple test during back surgery prevent nerve damage?
Knowledge-focused CompletedThis study looked at a technique that stimulates nerves during a specific type of spine surgery (XLIF) to see if it can quickly spot nerve problems. Researchers checked how well the method worked by comparing nerve signals during surgery with patients' nerve health up to six week…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated May 17, 2026 08:48 UTC
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Spine surgery blueprint: planning may boost outcomes
Knowledge-focused CompletedThis study looked at whether using special software to plan spine alignment before surgery leads to better results. It involved 306 adults having thoracolumbar fusion surgery. Researchers checked if the plan changed based on alignment feedback and if the final alignment matched t…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated May 17, 2026 08:47 UTC
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New tool watches nerves during spine screw placement
Knowledge-focused CompletedThis study looked at a device called NeuroVision that monitors nerve activity during spine surgery. Normally, surgeons check screw placement after the screw is in. This device lets them check as the screw goes in, aiming to catch problems early. The study involved 60 adults havin…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Computer model aims to predict posture after spine surgery
Knowledge-focused CompletedThis study tested a computer model that predicts the most comfortable posture a person will have after spinal fusion surgery. Researchers enrolled 200 adults who had already undergone thoracolumbar spinal fusion. The goal was to see if the model's predictions matched the patients…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Spine surgery nerve check: new method tested
Knowledge-focused CompletedThis study tested a new method to monitor nerves during lower back surgery. Researchers used surface electrodes to stimulate nerves above the surgical area and recorded muscle responses in the legs. The goal was to see if this approach is reliable and reproducible. 57 adults unde…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Massive spine surgery database aims to unlock better outcomes
Knowledge-focused CompletedThis study collected information from over 8,000 people who had spine surgery for conditions like degeneration, deformity, or trauma. Researchers gathered data on how well different surgeries worked and how patients recovered. The goal was to build a large database to help answer…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Spine surgery safety check: nerve monitors put to the test
Knowledge-focused CompletedThis study looked at how well nerve monitoring tools work during a type of spine surgery called XLIF. 323 adults with worn-out lower back discs took part. The goal was to see if these monitors can accurately detect nerve problems during the operation, helping surgeons avoid injur…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated May 08, 2026 12:02 UTC