Nuvasive
Clinical trials sponsored by Nuvasive, explained in plain language.
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New artificial disc could replace fusion for neck pain
Disease control CompletedThis study tested a new artificial disc called Simplify® for people with severe neck and arm pain from cervical degenerative disc disease. The trial involved 150 adults who received the disc and were compared to a historical group that had spinal fusion surgery. The goal was to s…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Artificial disc holds up over 5 years in neck pain study
Disease control CompletedThis study followed 145 people who received the Simplify Cervical Artificial Disc to treat neck problems caused by worn-out discs. Researchers checked if the disc was still working safely after 5 years, looking for pain improvement, device failures, or need for more surgery. The …
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New artificial disc could replace fusion for neck pain sufferers
Disease control CompletedThis study tested a new artificial disc called the Simplify Disc for people with two-level cervical disc disease causing arm pain, neck pain, or nerve problems. The trial involved 182 participants and compared the disc to standard fusion surgery. The goal was to see if the disc i…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Artificial disc shows promise in 5-Year neck pain study
Disease control CompletedThis study followed 291 patients for 5 years after receiving the Simplify Disc, an artificial disc for the neck. The goal was to see if the disc remains safe and effective over time. Researchers measured pain, nerve function, and whether any further surgeries were needed.
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New back surgery shows promise for disc disease sufferers
Disease control CompletedThis study tested a new type of spine surgery called ILIF for people with degenerative disc disease, a condition where spinal discs wear down causing pain and nerve issues. 77 adults over 40 who had not improved with other treatments received the surgery. Researchers measured cha…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Stem cell bone graft shows promise for back pain relief
Disease control CompletedThis study looked at whether a special bone graft called Osteocel Plus, which contains stem cells, helps the spine bones fuse together after surgery. It included 51 adults with degenerative disc disease who had not improved with other treatments. The goal was to see if this graft…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Minimally invasive back surgery may offer same benefits with fewer risks
Disease control CompletedThis study compared two surgical techniques for treating lumbar degenerative disc disease: traditional open surgery (open PLIF) and a newer, less invasive version (MAS PLIF). Researchers tracked complications and pain relief in 67 adults who needed spinal fusion. The goal was to …
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New bone graft shows promise in neck fusion surgery
Disease control CompletedThis study looked at a product called Osteocel Plus used during neck fusion surgery for people with degenerative disc disease. The goal was to see how well the bones fused together and how safe the product was. 182 adults were followed for 24 months after surgery. The results wer…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Stem cell bone graft shows promise for back pain relief
Disease control CompletedThis study tested Osteocel Plus, a bone graft material that contains stem cells, in 28 adults with degenerative disc disease who needed spinal fusion surgery. The goal was to see if it helps the spine bones fuse together as well as standard bone grafts. Researchers measured fusio…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Stem cell bone graft shows promise for back pain relief
Disease control CompletedThis study tested Osteocel Plus, a special bone graft that contains stem cells, in 19 people with degenerative disc disease who needed spinal fusion surgery. The goal was to see if the graft helps bones fuse together as well as the standard method using the patient's own bone. Th…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New bone graft shows promise in spine fusion surgery
Disease control CompletedThis study looked at using Osteocel Plus, a bone graft material, in a type of spine surgery called XLIF for people with degenerative disc disease and back pain. 104 adults aged 18-80 who needed fusion of one or two lower spine segments were enrolled. The main goal was to see how …
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New spine implants tested for safety in patients with back problems
Disease control CompletedThis study looked at the safety and performance of two types of expandable spine implants (MLX and XLX ACR) in 109 adults with degenerative disc disease, spondylolisthesis, or scoliosis. Researchers tracked complications, bone fusion, and improvement in nerve symptoms after surge…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New spine plate shows promise in fusion surgery study
Disease control CompletedThis study tested a new plate system used during spine fusion surgery in 75 adults with conditions like degenerative disc disease or scoliosis. The goal was to see if the plate is safe and helps bones fuse together properly. Researchers measured pain relief and fusion success ove…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New spinal implant shows promise in back surgery study
Disease control CompletedThis study looked at how safe and well a new spinal implant (Modulus ALIF System) works in 123 adults having back surgery. The patients had conditions like worn-out discs or slipped vertebrae. The main goals were to check for complications and see if the bones fused properly afte…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New 3D-Printed spine implant shows promise in small study
Disease control CompletedThis study tested a new 3D-printed titanium implant for spine fusion surgery in 36 adults with degenerative disc disease, spondylolisthesis, or scoliosis. The implant is designed to help bones in the spine grow together after surgery. Researchers looked at safety, how well the bo…
Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New putty may replace Patient's own bone in spine surgery
Disease control CompletedThis study tested whether a man-made bone graft putty (AttraX) works as well as using the patient's own bone for spinal fusion surgery. 45 adults with degenerative spine conditions were enrolled. The main goal was to see if the putty helped bones fuse together just as well as the…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New artificial disc could keep neck moving after surgery
Disease control CompletedThis study tested a new artificial disc called NeoDisc against standard fusion surgery (ACDF) in 488 people with a damaged disc in the neck. The goal was to see if NeoDisc is as safe and effective at relieving pain and improving function over two years. Participants were randomly…
Phase: NA • Sponsor: NuVasive • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Spine surgery showdown: which approach helps patients recover faster?
Symptom relief CompletedThis study compared two types of spine surgery (XLIF and TLIF) in 55 adults with a slipped vertebra causing pain and leg symptoms. The goal was to see which procedure led to better function and less pain over two years. Results could help doctors choose the best surgical approach…
Sponsor: NuVasive • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Real-Time screw check could prevent nerve damage in spine surgery
Knowledge-focused CompletedThis study tested a device called NeuroVision that monitors nerve activity during spine surgery. It has a new feature that checks if screws are placed correctly as they go in, rather than after. The goal was to see if this real-time check helps surgeons avoid nerve problems. The …
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Spine surgery safety check: nerve monitoring put to the test
Knowledge-focused CompletedThis study looked at how well nerve monitoring works during a type of spine surgery called XLIF. It involved 323 adults with worn-out discs in their lower back. The goal was to see if the monitoring could accurately detect nerve problems during the operation.
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Massive spine surgery database aims to unlock better treatments
Knowledge-focused CompletedThis study collected information from over 8,000 people who had spine surgery for conditions like degeneration, deformity, or trauma. Researchers gathered X-ray and health data to learn which treatments work best for different patients. The goal was to build a database to answer …
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Spine surgery gets a High-Tech planning boost
Knowledge-focused CompletedThis study looked at whether using a computer program to plan spine surgery helps surgeons get better results. It included 306 adults having back or spine fusion surgery. The goal was to see if the planning software helped the surgeon achieve the desired spine alignment after sur…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New nerve check during back surgery could prevent damage
Knowledge-focused CompletedThis study tested a method to monitor nerve health during a specific type of spine surgery called XLIF. Researchers used mild electrical stimulation on the lower back nerves during surgery and checked if changes in nerve signals could predict nerve problems after surgery. 324 adu…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Can a computer predict your posture after back surgery?
Knowledge-focused CompletedThis study tested whether a computer model can accurately predict a patient's posture after spinal fusion surgery. Researchers used data from 200 adults who had thoracolumbar spinal fusion and compared the model's predictions to their actual posture at follow-up. The goal is to h…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Spine surgery breakthrough: new nerve monitoring method tested
Knowledge-focused CompletedThis study tested a new method to monitor nerves during spine surgery for degenerative lumbar disc disease. Researchers used surface electrodes on the skin to stimulate nerves in the lower back and record muscle responses in the legs. The goal was to see if this approach is relia…
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC