New artificial disc could keep neck moving after surgery

NCT ID NCT00478088

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new artificial disc called NeoDisc against standard fusion surgery (ACDF) in 488 people with a damaged disc in the neck. The goal was to see if NeoDisc is as safe and effective at relieving pain and improving function over two years. Participants were randomly assigned to receive either the artificial disc or fusion, and researchers tracked neck disability, complications, and nerve function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

NeoDisc artificial disc replacement device

What this could lead to

If successful, NeoDisc could offer a motion-preserving alternative to fusion surgery, potentially reducing long-term neck stiffness and adjacent disc problems.

What could go wrong

This is a completed trial, but results may not apply to all patients. Risks include device failure, need for revision surgery, or no better outcomes than standard fusion.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Capital Neurosurgery

    Raleigh, North Carolina, 27609, United States

  • Center for Advanced Orthopaedics/Adena Health Pavillon

    Chillicothe, Ohio, 45601, United States

  • Central Ohio Neurological Surgeons

    Westerville, Ohio, 43081, United States

  • Central Texas Spine Institute

    Austin, Texas, 78731, United States

  • Coastal Spine

    Mount Laurel, New Jersey, 08054, United States

  • Diagnostic and Interventional Surgical Center

    Marina del Rey, California, 90245, United States

  • Florida Research Network, LLC

    Gainesville, Florida, 32605, United States

  • Florida Spine Specialists

    Fort Lauderdale, Florida, 33308, United States

  • Lyerly Baptist

    Jacksonville, Florida, 32207, United States

  • Neurological Associates

    Columbus, Ohio, 43221, United States

  • OAD Orthopaedics

    Warrenville, Illinois, 60555, United States

  • Optim Healthcare

    Savannah, Georgia, 31405, United States

  • OrthoIndy

    Indianapolis, Indiana, 46278, United States

  • Orthopedic Spine Associates

    Eugene, Oregon, 97401, United States

  • Rocky Mountain Spine Arthroplasty (RMA Ortho)

    Loveland, Colorado, 80538, United States

  • Salt Lake Orthopaedic Clinic

    Salt Lake City, Utah, 82124, United States

  • San Diego Center for Spinal Disorders

    La Jolla, California, 92037, United States

  • Southern Oregon Orthopedics

    Medford, Oregon, 97504, United States

  • Spine Colorado / Durango Orthopedic Associates

    Durango, Colorado, 81301, United States

  • Spine Midwest, Inc

    Jefferson City, Missouri, 65101, United States

  • The Spine Institute

    Santa Monica, California, 90404, United States

  • Western Regional Spine Center for Brain and Spine Surgery

    Las Vegas, Nevada, 89109, United States