New artificial disc could keep neck moving after surgery

NCT ID NCT00478088

Completed Disease control Sponsor: NuVasive Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new artificial disc called NeoDisc against standard fusion surgery (ACDF) in 488 people with a damaged disc in the neck. The goal was to see if NeoDisc is as safe and effective at relieving pain and improving function over two years. Participants were randomly assigned to receive either the artificial disc or fusion, and researchers tracked neck disability, complications, and nerve function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NeoDisc artificial disc replacement device
What this could lead to: If successful, NeoDisc could offer a motion-preserving alternative to fusion surgery, potentially reducing long-term neck stiffness and adjacent disc problems.
What could go wrong: This is a completed trial, but results may not apply to all patients. Risks include device failure, need for revision surgery, or no better outcomes than standard fusion.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cervical disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL DISC DEGENERATIVE DISORDER

Contacts and locations

Locations

Capital Neurosurgery

Raleigh, North Carolina, 27609, United States
Center for Advanced Orthopaedics/Adena Health Pavillon

Chillicothe, Ohio, 45601, United States
Central Ohio Neurological Surgeons

Westerville, Ohio, 43081, United States
Central Texas Spine Institute

Austin, Texas, 78731, United States
Coastal Spine

Mount Laurel, New Jersey, 08054, United States
Diagnostic and Interventional Surgical Center

Marina del Rey, California, 90245, United States
Florida Research Network, LLC

Gainesville, Florida, 32605, United States
Florida Spine Specialists

Fort Lauderdale, Florida, 33308, United States
Lyerly Baptist

Jacksonville, Florida, 32207, United States
Neurological Associates

Columbus, Ohio, 43221, United States
OAD Orthopaedics

Warrenville, Illinois, 60555, United States
Optim Healthcare

Savannah, Georgia, 31405, United States
OrthoIndy

Indianapolis, Indiana, 46278, United States
Orthopedic Spine Associates

Eugene, Oregon, 97401, United States
Rocky Mountain Spine Arthroplasty (RMA Ortho)

Loveland, Colorado, 80538, United States
Salt Lake Orthopaedic Clinic

Salt Lake City, Utah, 82124, United States
San Diego Center for Spinal Disorders

La Jolla, California, 92037, United States
Southern Oregon Orthopedics

Medford, Oregon, 97504, United States
Spine Colorado / Durango Orthopedic Associates

Durango, Colorado, 81301, United States
Spine Midwest, Inc

Jefferson City, Missouri, 65101, United States
The Spine Institute

Santa Monica, California, 90404, United States
Western Regional Spine Center for Brain and Spine Surgery

Las Vegas, Nevada, 89109, United States

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