New artificial disc could replace fusion for neck pain

NCT ID NCT02667067

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new artificial disc called Simplify® for people with severe neck and arm pain from cervical degenerative disc disease. The trial involved 150 adults who received the disc and were compared to a historical group that had spinal fusion surgery. The goal was to see if the artificial disc is as safe and effective as fusion, while allowing more natural neck movement.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Simplify® cervical artificial disc (a medical device)

What this could lead to

If successful, this artificial disc could offer a motion-preserving alternative to spinal fusion for people with severe neck and arm pain.

What could go wrong

This is a completed trial comparing a device to an older surgery. Results may not apply to all patients, and device-related risks like failure or need for additional surgery remain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Study site

    La Jolla, California, United States

  • Study site

    Orange, California, United States

  • Study site

    Santa Monica, California, United States

  • Study site

    Thornton, Colorado, United States

  • Study site

    Sarasota, Florida, United States

  • Study site

    Evanston, Illinois, United States

  • Study site

    Carmel, Indiana, United States

  • Study site

    Paducah, Kentucky, United States

  • Study site

    Shreveport, Louisiana, United States

  • Study site

    Egg Harbor, New Jersey, United States

  • Study site

    Lockport, New York, United States

  • Study site

    Charlotte, North Carolina, United States

  • Study site

    Addison, Texas, United States

  • Study site

    Plano, Texas, United States

  • Study site

    Tyler, Texas, United States

  • Study site

    Reston, Virginia, United States