Artificial disc shows promise in 5-Year neck pain study
NCT ID NCT04980378
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study followed 291 patients for 5 years after receiving the Simplify Disc, an artificial disc for the neck. The goal was to see if the disc remains safe and effective over time. Researchers measured pain, nerve function, and whether any further surgeries were needed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Simplify Disc (artificial cervical disc)
What this could lead to
If successful, this could confirm that the Simplify Disc is a safe and effective long-term option for treating cervical disc disease, potentially reducing pain and improving function.
What could go wrong
This is a post-approval study confirming earlier results, not a new breakthrough. Risks include implant failure, need for additional surgery, or no long-term benefit for some patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Buffalo Spine Surgery
Lockport, New York, 14094, United States
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Carolina Neurosurgery and Spine Associates
Charlotte, North Carolina, 28204, United States
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Connecticut Orthopaedic Specialists
Hamden, Connecticut, 06518, United States
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Indiana Spine Group
Carmel, Indiana, 46032, United States
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Kennedy-White Orthopedic Center
Sarasota, Florida, 34232, United States
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NorthShore University Health System
Evanston, Illinois, 60201, United States
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Oregon Neurosurgery
Springfield, Oregon, 97477, United States
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Orthopaedic Education and Research Institute of Southern California
Orange, California, 92868, United States
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Orthopaedic Institute of Western Kentucky
Paducah, Kentucky, 42003, United States
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Parkview Research Center
Fort Wayne, Indiana, 46845, United States
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Spine Education and Research Foundation
Thornton, Colorado, 80229, United States
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Spine Institute of Louisiana
Shreveport, Louisiana, 71101, United States
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Texas Back Institute
Plano, Texas, 75093, United States
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Texas Spine Consultants
Addison, Texas, 75001, United States
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The Disc Replacement Center
West Jordan, Utah, 84088, United States
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The Spine Institute for Spine Restoration
Santa Monica, California, 90403, United States
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Virginia Spine Institute
Reston, Virginia, 20191, United States
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William Beaumont Hospital Research Institute
Royal Oak, Michigan, 48073, United States