New bone graft shows promise in spine fusion surgery

NCT ID NCT00948532

Completed Disease control Sponsor: NuVasive Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at using Osteocel Plus, a bone graft material, in a type of spine surgery called XLIF for people with degenerative disc disease and back pain. 104 adults aged 18-80 who needed fusion of one or two lower spine segments were enrolled. The main goal was to see how many achieved solid bone fusion within 24 months after surgery, and how long it took. Results were compared to historical data for other graft options.

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Conditions

The condition(s) this trial relates to.

Back Pain intervertebral disk degenerative disorder lumbar disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACK PAIN DEGENERATIVE DISC DISEASE

Contacts and locations

Locations

Broward Spine Institute

Hollywood, Florida, 33021, United States
Buffalo Spine Surgery, Kenmore Mercy

Lockport, New York, 14094, United States
Columbia Orthopaedic Group, Boone Hospital Center

Columbia, Missouri, 65205, United States
Duke University Medical Center

Chapel Hill, North Carolina, 27710, United States
Indiana Center for Neurosurgery

Indianapolis, Indiana, 46219, United States
Pinnacle Orthopaedics, Wellstone Kennestone Hospital

Marietta, Georgia, 30060, United States
Shiley Center for Orthopaedic, Scripps Green Hospital

La Jolla, California, 92037, United States
South Florida Spine Institute, Mount Sinai Medical Center

Miami Beach, Florida, 33140, United States
Southeastern Spine Center, Doctors Hospital of Sarasota

Sarasota, Florida, 34232, United States
Spine Midwest, St. Mary's Health Center

Jefferson City, Missouri, 65101, United States
The Spine Center of DuPage Medical Group, Edward Hospital

Naperville, Illinois, 60540, United States
USF, Tampa General Hospital

Tampa, Florida, 33606, United States
Western Regional Center for Brain & Spine Surgery, Surgery Center of S. Nevada

Las Vegas, Nevada, 89109, United States

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