Minia University

This trial tests whether 3D-printed metal retainers (made from cobalt-chromium or titanium) work better than the standard twisted-wire retainer at keeping teeth from shifting after braces. Thirty-six adults who have just finished orthodontic treatment will receive one of the thre…

This trial tests whether preserving the hernia sac as a living flap and stitching it under the mesh can reduce wound and mesh problems after complex ventral hernia repair where the defect has a bony edge. Half of the 180 participants will receive the standard repair plus the sac …

This study compares two ways of stitching the uterine wall after laparoscopic isthmocele repair: vertical closure (along the uterus) vs. transverse closure (across it). The goal is to see which method leads to a thicker, stronger scar and better symptom relief. The trial will enr…

This study tests a new surgical procedure (laparoscopic clipping of certain blood vessels) against a standard hormonal IUD (Mirena) to see which better reduces heavy monthly bleeding in women with enhanced myometrial vascularity. About 56 women aged 18-45 with confirmed diagnosis…

This study tests if a less invasive procedure called partial pulpotomy using CGF (a blood concentrate) can control pain and inflammation in severely decayed permanent molars as well as standard root canal treatment. It will involve 60 adolescents aged 11-17 with intense tooth pai…

This study compares two laparoscopic surgeries—Nissen fundoplication and Hill-Snow repair—for children with hiatal hernia and severe acid reflux. Forty participants will be randomly assigned to one surgery, and doctors will use a camera (endoscope) before, during, and after to ch…

This early-phase study tests whether a low dose of oral amlodipine can prevent kidney damage caused by contrast dye in diabetic patients in the intensive care unit. The trial will enroll 40 adults with diabetes and normal kidney function who are stable enough for the procedure. R…

This study compares two treatments for caesarean scar pregnancy, a rare but serious condition where a pregnancy implants in a previous C-section scar. Forty-two women will receive either ultrasound-guided surgical removal or a combination of local and systemic methotrexate. The g…

This study compares two cavity removal methods in 144 adults with deep cavities and reversible pulpitis (tooth nerve inflammation that can heal). One method removes all decay, the other leaves some near the nerve. Researchers will check pain, tooth vitality, and X-rays over 12 mo…

This trial compares two different file systems used during root canal treatment for infected lower molars. The goal is to see whether a newer, minimally invasive single-file system leads to less pain after the procedure than the standard Wave One Gold system. Adults with a specif…

This study tests whether natural medicines (propolis and green tea extract) placed inside the tooth can reduce pain and sudden flare-ups after a root canal retreatment. Forty adults with a failed root canal on a single-rooted tooth will be randomly assigned to get either the stan…

This trial tests two different nerve block methods to control pain after laparoscopic gallbladder removal. Sixty adults undergoing elective surgery will receive either a newer single-puncture block or an external oblique intercostal plane block, while a control group gets only st…

This study will compare two types of nerve blocks for pain relief after knee arthroscopy. 72 adults scheduled for knee surgery will receive either an adductor canal block or a genicular nerve block, both combined with an IPACK block. The goal is to see which method delays the nee…

This study tests whether adding a technique called vascular deformation mapping (VDM) to standard CT scans can better predict liver failure after major liver surgery. Researchers will analyze routine preoperative CT images from over 1,000 adults undergoing removal of at least thr…

This study follows 420 adults undergoing abdominal wall reconstruction with mesh to identify which patient, surgical, and recovery factors most strongly predict a mesh infection within 90 days. Researchers will track 18 potential risk factors and use statistical analysis to pinpo…

This study will measure the thickness of the carotid artery wall in 100 adults on hemodialysis. The goal is to see how traditional heart risk factors (like high blood pressure and diabetes) and dialysis-specific factors (like treatment length) relate to artery thickness. No new t…

This study looks at how fear of movement (kinesiophobia) affects daily function in people with rheumatoid arthritis. Researchers will compare 200 RA patients with 200 healthy volunteers to understand links between fear, pain, fatigue, mood, and muscle loss. The goal is to find no…

This study looks at whether sleep problems before surgery and a brain chemical called melanin-concentrating hormone (MCH) are linked to delayed mental recovery in adults aged 65 and older after spinal anesthesia. Researchers will measure MCH in spinal fluid and blood, and compare…

This study will use Doppler ultrasound to measure blood flow in the uterine artery before and after removing a molar pregnancy. The goal is to see if these measurements can predict which patients will develop persistent gestational trophoblastic neoplasia, a type of cancer. Resea…

This study will compare three devices used to help breathing tubes into the windpipe (intubation) in ICU patients. Doctors wearing face shields will use either a C-Mac video laryngoscope, a Pentax video laryngoscope, or a traditional Macintosh laryngoscope. The main goal is to se…

This study will observe 64 adults with sepsis to see if dapagliflozin, a diabetes medicine, reduces inflammation and improves organ function. Researchers will measure inflammatory markers and track severity of illness and survival. The goal is to learn if this drug could be a hel…