Milton S. Hershey Medical Center
Clinical trials sponsored by Milton S. Hershey Medical Center, explained in plain language.
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Berry lozenges may shield Smokers' DNA
Disease control CompletedThis study looked at whether black raspberry lozenges could reduce DNA damage in mouth cells caused by smoking. 69 adult smokers took the lozenges for several weeks. The goal was to see if the berries could lower harmful chemical markers linked to oral cancer. Results may help fi…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Can a simple supplement tame PCOS hormones?
Disease control CompletedThis study tested whether inositol, a natural dietary supplement, can lower high testosterone levels in women with polycystic ovary syndrome (PCOS). 154 women took either a placebo or one of three doses of inositol powder for a set period. Researchers measured changes in testoste…
Phase: PHASE2 • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Fatty liver patients try VR diet coach
Disease control CompletedThis study tested whether a virtual reality (VR) diet program is a practical way to help people with fatty liver disease lose weight. Twenty adults with fatty liver were randomly assigned to receive diet counseling either in person or through a VR headset. The VR program, called …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Can exercise coaching keep seniors safe from falls?
Prevention CompletedThis study tested two approaches to prevent serious fall injuries in older adults (65+) who had a prior bone fracture. One group received enhanced usual care, while the other received exercise coaching. Researchers tracked serious fall injuries, falls, and overall health over 36 …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Prevention
Last updated Jun 27, 2026 12:30 UTC
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Can a common malaria drug stop lupus before it starts?
Prevention CompletedThis study tested whether hydroxychloroquine, a drug already used for lupus, could slow or prevent the disease in 187 people who had early signs but not full lupus. Participants received either the drug or a placebo for up to two years. Researchers tracked lupus symptoms, immune …
Phase: PHASE2 • Sponsor: Milton S. Hershey Medical Center • Aim: Prevention
Last updated Jun 26, 2026 18:33 UTC
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Music as medicine? tunes may soothe pain during back procedures
Symptom relief CompletedThis study looked at whether playing music of a patient's choice during lumbar interventional procedures (like epidural steroid injections) could reduce pain and anxiety in people with chronic back pain. Thirty adults were randomly assigned to hear music or no music during their …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Eyedrop lifts droopy eyelids after facial paralysis?
Symptom relief CompletedThis study tested an FDA-approved eyedrop (oxymetazoline 0.1%) in 36 adults with eyelid droop caused by facial nerve miswiring after paralysis. The goal was to see if the drop could temporarily raise the eyelid, improve vision, and reduce abnormal muscle spasms. Researchers measu…
Phase: PHASE3 • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Which lens helps you see better after cataract surgery?
Symptom relief CompletedThis study looked at two different artificial lenses used during cataract surgery to see which one gives better vision at near, middle, and far distances. 80 adults with cataracts received one of the two lenses. The goal was to find out if one lens helps people see better without…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Shocking away the pain: TENS device tested for endometriosis flares
Symptom relief CompletedThis study tested whether a TENS unit, a small device that sends mild electrical pulses through the skin, can reduce pain during endometriosis flares. Forty women with surgically confirmed endometriosis tracked their pain for three months without the device, then for three months…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Mindfulness may lower blood sugar in stressed diabetes patients
Symptom relief CompletedThis study tested whether an online mindfulness program could help adults with type 1 or type 2 diabetes lower their blood sugar. Over 300 participants with high stress and poor glucose control were randomly assigned to either an 8-week Mindfulness-Based Stress Reduction course o…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Can a phone app monitor ALS progression from home?
Knowledge-focused CompletedThis study is testing whether a smartphone app can reliably track speech and swallowing problems in people with ALS. Participants will record their voice and swallowing sounds at home each week using the app. The goal is to see if this remote monitoring is feasible and accurate c…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Wearable sensors monitor ALS progression in new study
Knowledge-focused CompletedThis study tests whether wearable sensors and digital home tasks can track changes in movement, speech, and falls in people with ALS. About 20 participants will wear neck and wrist sensors and complete speech and handwriting tests over 48 weeks. The goal is to see if these digita…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Tablet tests could track ALS progression through speech and handwriting
Knowledge-focused CompletedThis study explores whether digital tools on a tablet can measure changes in speech and handwriting in people with motor neuron diseases like ALS. Participants complete a single session of speaking and tracing tasks. Researchers compare results between patients and healthy contro…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Herbal supplement tested for safety in prostate cancer – no cure expected
Knowledge-focused CompletedThis early-stage study tested the safety of a single dose of an Angelica herbal supplement (AGN-Cogni.Q) in 12 men aged 40 and older with prostate cancer. Researchers checked heart health and blood tests for any side effects, and measured how the supplement's compounds move throu…
Phase: PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Can a phone app help fight fatty liver disease?
Knowledge-focused CompletedThis study tested whether a mobile health app called EL-FIT could help people with nonalcoholic steatohepatitis (NASH) exercise safely at home. Seventeen adults with NASH used the app and a Fitbit to do daily exercise as they wished. The main goal was to see if it was feasible an…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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BINGO for better health: fun games aim to boost cancer awareness in black communities
Knowledge-focused CompletedThis study tested whether playing educational BINGO games could help Black adults learn about cancer and clinical trials. 54 participants played BINGO in a relaxed setting and answered surveys to measure their knowledge and engagement. The goal was to build trust and find better …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Ancient herb put to the test: can angelica root supercharge immunity?
Knowledge-focused CompletedThis study tested whether a dietary supplement made from Korean Angelica root (Cogni.Q) can increase the number of key immune cells in the blood. Fifteen healthy adults took either the supplement or a placebo to see if the herb truly boosts neutrophils (which fight bacteria) and …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Rural clinics test video training to boost HPV shots in teens
Knowledge-focused CompletedThis study tested whether training rural doctors through video sessions (Project ECHO) could increase HPV vaccination rates in 11-14 year olds. Some clinics also sent recall notices to parents who initially declined the vaccine. The goal was to see if these strategies help more t…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Blood test may help overcome barriers to colon cancer screening
Knowledge-focused CompletedThis completed study with 297 participants examined if offering a blood-based screening test (Guardant Shield) encourages people who previously avoided stool tests or colonoscopy to get screened for colorectal cancer. Participants were adults aged 45-75 at average risk who had no…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Blood test may boost colorectal cancer screening in reluctant patients
Knowledge-focused CompletedThis study tested whether offering a simple blood test instead of a colonoscopy or stool test would encourage more people to get screened for colorectal cancer. Researchers enrolled 297 adults aged 45-75 who had previously skipped or refused traditional screening. The goal was to…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New strategy aims to boost colon cancer screening in underserved communities
Knowledge-focused CompletedThis study tested a program to increase colorectal cancer screening and follow-up in federally qualified health centers, which serve many low-income and uninsured people. The program included education for doctors and staff, patient reminders, and help navigating care. Researcher…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Could a gel spacer replace needle markers in prostate radiation?
Knowledge-focused CompletedThis study tested whether a special gel spacer placed near the rectum can help doctors aim radiation more accurately for prostate cancer. Seventeen men who already had the spacer and small metal markers (fiducials) were included. Doctors compared how well the gel spacer worked fo…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Robotic coaches could cut hospital infections by training doctors better
Knowledge-focused CompletedThis study tested robotic training devices (DHRT and DHRT+) to teach surgical residents how to insert central venous catheters. Over 770 residents from two medical centers used the devices during their standard training. Researchers then checked patient records to see if the new …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Flavored vapes may rewire Brain's reward system
Knowledge-focused CompletedThis study looked at whether flavor chemicals in e-cigarettes can make them more addictive by changing brain function. 36 regular tobacco users (ages 21-60) had their brain activity measured while vaping, and their puffing behavior was tracked over 10 days. The goal was to unders…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Warm baths may boost walking ability in PAD patients
Knowledge-focused CompletedThis study tested whether sitting in a warm bath (38-41°C) for up to 30 minutes could reduce blood pressure spikes during exercise in 33 people with peripheral artery disease (PAD). Participants walked on a treadmill, and researchers measured walking time, blood pressure, and hea…
Phase: EARLY_PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:30 UTC
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Could Low-Nicotine smokes plus E-Cigs cut harm for mentally ill smokers?
Knowledge-focused CompletedThis study looked at whether using very low nicotine cigarettes along with nicotine-containing e-cigarettes can reduce harmful chemical exposure in smokers with mental health conditions. 88 participants were assigned to different combinations of cigarettes and e-cigarettes. The m…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:59 UTC