Milton S. Hershey Medical Center
Clinical trials sponsored by Milton S. Hershey Medical Center, explained in plain language.
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Rural clinics boost HPV vaccination with simple training and reminders
⭐️ VACCINE ⭐️ CompletedThis study tested two ways to help rural doctors increase HPV vaccination among 11-14 year olds. One group of clinics trained doctors to make strong vaccine recommendations and answer parents' questions. Another group added reminder notices for parents who initially said no. The …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: ⭐️ VACCINE ⭐️
Last updated May 17, 2026 03:28 UTC
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Inositol supplement shows promise for PCOS hormone imbalance
Disease control CompletedThis study tested whether inositol, a natural supplement, can lower high testosterone levels in women with Polycystic Ovary Syndrome (PCOS). 154 women with PCOS took different doses of inositol to see which dose works best. The goal is to improve hormone balance and reduce sympto…
Phase: PHASE2 • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 17, 2026 03:24 UTC
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Virtual reality diet coach helps fight fatty liver
Disease control CompletedThis study tested a virtual reality (VR) diet program for people with fatty liver disease. The program, called IVAN, teaches healthy eating through an interactive VR experience. 20 adults used the program along with video counseling to see if it could help them lose weight and ea…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 04, 2026 16:18 UTC
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Can a malaria drug stop lupus before it starts?
Prevention CompletedThis study tested whether hydroxychloroquine, a medicine used for malaria, can slow down or prevent lupus in people who show early signs of the disease. 187 participants with mild symptoms and positive antibody tests were randomly given either the drug or a placebo. Researchers t…
Phase: PHASE2 • Sponsor: Milton S. Hershey Medical Center • Aim: Prevention
Last updated May 15, 2026 11:56 UTC
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Exercise coaching may keep seniors on their feet after a fracture
Prevention CompletedThis study looked at whether personalized exercise coaching could reduce serious fall injuries in older adults (65+) who had already broken a bone from a fall. Over 1,100 participants were split into two groups: one received enhanced usual care, the other got exercise coaching. R…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Prevention
Last updated May 11, 2026 20:50 UTC
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Eye drop offers new hope for droopy eyelids after facial paralysis
Symptom relief CompletedThis study tested an FDA-approved eye drop (oxymetazoline) to help people with droopy eyelids after facial paralysis. The droopiness happens because nerves grow back incorrectly, causing unwanted muscle movements. The study included 36 adults and measured changes in eyelid positi…
Phase: PHASE3 • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 17, 2026 03:29 UTC
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Which lens helps you see better? new study compares two popular implants
Symptom relief CompletedThis study looked at two different artificial lens implants used during cataract surgery to see which one gives better vision at near, middle, and far distances. About 80 adults with cataracts received one of the two lenses. The goal was to find out if one lens helps people see b…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 17, 2026 03:28 UTC
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TENS device tested for endometriosis flare pain relief
Symptom relief CompletedThis study looked at whether a TENS unit, a small device that sends gentle electrical pulses through the skin, can help reduce pain during endometriosis flare-ups. Forty women with surgically confirmed endometriosis tracked their pain, medication use, and bleeding for three month…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Mindfulness may lower blood sugar in stressed diabetes patients
Symptom relief CompletedThis study tested whether a 6-month online mindfulness program could help adults with uncontrolled type 1 or type 2 diabetes lower their blood sugar. Over 300 participants were randomly assigned to either mindfulness training or a stress management education class. The main goal …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Soothing sounds: music may ease pain and nerves during back treatments
Symptom relief CompletedThis study looked at whether playing music during common back pain procedures (like injections) can help lower patients' pain and anxiety. Thirty adults with chronic lower back pain took part. Researchers measured anxiety and pain scores before and after the procedure, comparing …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 13, 2026 15:59 UTC
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Angelica herb supplement put to the test in prostate cancer patients
Knowledge-focused CompletedThis early-stage study tested the safety and how the body processes a single dose of an Angelica herbal supplement (AGN-Cogni.Q) in 12 men aged 40 and older with prostate cancer. Researchers checked heart health and blood tests for any side effects, and measured levels of the sup…
Phase: PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:32 UTC
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Could a gel replace metal markers in prostate radiation?
Knowledge-focused CompletedThis study looked at whether a special gel placed near the rectum can help doctors aim radiation more accurately for prostate cancer. Seventeen men who already had the gel and small metal markers were included. The goal was to see if the gel could replace the markers for daily al…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:32 UTC
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Can heat help PAD patients walk longer?
Knowledge-focused CompletedThis study looked at whether heat exposure can change how the body responds to exercise in people with peripheral artery disease (PAD). Researchers measured walking time, blood pressure, and heart rate in 33 participants. The goal was to understand if heat can reduce the stress o…
Phase: EARLY_PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:31 UTC
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Blood test may boost colorectal cancer screening in underserved groups
Knowledge-focused CompletedThis study aimed to understand if offering a simple blood test for colorectal cancer screening would encourage more people to get screened. Researchers surveyed 297 adults aged 45-75 who had previously avoided standard screening methods like colonoscopy or stool tests. The goal w…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:31 UTC
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Herbal immune boost? small study tests angelica root against placebo
Knowledge-focused CompletedThis study tested whether a dietary supplement made from Korean Angelica root (Cogni.Q) can increase certain immune cells. Fifteen healthy adults took either the supplement or a dummy pill (placebo) to see if the supplement raised levels of neutrophils (which fight bacteria) and …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:29 UTC
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Blood test may boost colorectal cancer screening in reluctant patients
Knowledge-focused CompletedThis study looked at whether offering a blood-based screening test could encourage people who had previously avoided colonoscopy or stool tests to get screened for colorectal cancer. Researchers enrolled 297 adults aged 45-75 who had not completed a recommended screening. The goa…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:26 UTC
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New program aims to boost cancer screening in underserved communities
Knowledge-focused CompletedThis study tested a multi-level program to increase colorectal cancer screening and follow-up in federally qualified health centers serving disadvantaged populations. The program included provider education, reminders, and patient navigation. The goal was to see if these combined…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:25 UTC
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Can low nicotine cigarettes plus E-Cigs reduce harm for smokers?
Knowledge-focused CompletedThis study tested whether using very low nicotine cigarettes along with nicotine-containing e-cigarettes could reduce exposure to harmful chemicals in smokers with mental health conditions. 88 smokers took part. The goal was to measure changes in cancer-causing substances and smo…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 03:23 UTC
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Flavored vapes may boost addiction by altering brain activity
Knowledge-focused CompletedThis study looked at whether flavor chemicals in e-cigarettes can make them more addictive by changing brain function. 36 adults who regularly use tobacco products took part. Researchers measured brain activity and puffing behavior to understand how flavors influence addiction ri…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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BINGO for better health: fun game aims to boost cancer trial diversity
Knowledge-focused CompletedThis study tested whether playing BINGO could help educate Black adults about cancer and clinical trials. Researchers hosted BINGO sessions with cancer information for 54 participants. The goal was to build trust and see if this fun approach increases awareness and willingness to…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Berry lozenges may shield Smokers' mouth cells from DNA harm
Knowledge-focused CompletedThis study looked at whether black raspberry lozenges could lower DNA damage in mouth cells caused by smoking. Sixty-nine adult smokers took the lozenges over several weeks. Researchers measured specific DNA adducts (signs of damage) to see if the berries had a protective effect.
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Can a phone app help NASH patients get fit?
Knowledge-focused CompletedThis study tested whether a mobile health exercise program, called EL-FIT, is practical and safe for people with NASH (a type of fatty liver disease). Seventeen adults with NASH used the app to follow exercise sessions at home. The main goal was to see if at least half of them co…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC
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Robot coach helps new doctors avoid mistakes
Knowledge-focused CompletedThis study tested whether a robotic training device helps new medical residents learn how to insert central lines (a type of IV) more safely. Over 700 residents trained with the device, and researchers checked patient records to see if complication and infection rates changed. Th…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:49 UTC