Milton S. Hershey Medical Center

This study is testing if a lower dose of a drug called cyclophosphamide, given after a stem cell transplant, can safely prevent a serious complication called graft-versus-host disease (GVHD) while still helping control blood cancers. It will involve 41 adults with various blood c…

This study is testing if adding a drug called eflornithine (DFMO) to standard chemotherapy can help young people with Ewing sarcoma or osteosarcoma. It aims to see if this combination helps patients live longer without their cancer coming back. The trial will enroll about 406 par…

This study is testing a new ultrasound-guided system to improve the placement of a temporary drain in the brain for patients with hydrocephalus (fluid buildup). The goal is to see if this tool helps doctors place the drain correctly on the first try, reducing the need for multipl…

This study is testing if a short infusion of amino acids given during heart surgery can help prevent a common and serious complication called acute kidney injury. Researchers will compare two groups of adult patients having planned heart surgery: one group gets standard care, and…

This study is testing a pilot program that coaches young adult cancer survivors on how to communicate better with their friends and peers. The goal is to see if improving these conversations can help reduce feelings of anxiety, depression, and social isolation after cancer treatm…

This study compares two different ways to position the needle during a common back pain procedure called radiofrequency ablation. Researchers want to see if a newer, more direct needle placement provides better pain relief than the traditional angled approach. The study will invo…

This small, early-stage study is testing if a commercially available hemp oil containing CBG and CBD is safe and might help reduce symptoms of nerve damage caused by chemotherapy. It will involve 12 adults who have finished platinum-based chemo for gastrointestinal cancers and st…

This study tests whether a simple support program can help reduce stress for people caring for loved ones with dementia. Participants who previously took part in an observational study will receive six weeks of educational text messages or emails about caregiving and stress manag…

This study is testing whether a procedure called serial dermabrasion can safely make scars look better for people who have had reconstructive head and neck surgery. It will involve 40 adults who have a healed skin flap or donor site scar. The researchers will treat only half of e…

This study is testing a behavioral program designed to improve sleep and daily body clock rhythms in autistic adults. It aims to help 24 participants who have long-term sleep problems. The main goal is to see if the program improves overall sleep health, including sleep timing, q…

This study is testing whether collagen shields (special contact lens-like bandages) help reduce pain for people with corneal abrasions (eye scratches) treated in the emergency room. Researchers will compare pain levels and pain medication use in 60 patients who receive either the…

This small pilot study is testing whether automated, personalized phone messages can help stroke survivors become more physically active. It will enroll 50 adults who had a stroke 3 months to 3 years ago and are currently inactive. The main goal is to see if this automated approa…

This early research study aims to understand how low estrogen levels after menopause might increase a woman's risk for heart disease. Researchers will measure blood pressure, nerve activity, and inflammation markers in 20 healthy postmenopausal women. The goal is to gather basic …

This early study aims to understand if vitamin B6 can help control a sharp rise in blood pressure that happens during exercise in people with poor leg circulation (Peripheral Artery Disease). Researchers will study 30 healthy volunteers to see if blocking a specific protein in ne…

This study is preparing to test if a specially adapted conversation game can help members of the Washoe Tribe talk about and plan for future medical care and end-of-life wishes. Researchers will work with about 108 adult tribe members to see if the game is a good fit for their cu…

This study aims to measure the levels of harmful, cell-damaging chemicals produced when cigarette smokers use little cigars. Researchers will enroll 50 daily cigarette smokers who have never used little cigars. Participants will try different little cigar products and their usual…