Milton S. Hershey Medical Center
Clinical trials sponsored by Milton S. Hershey Medical Center, explained in plain language.
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Can a healthy diet prolong the 'Honeymoon Phase' in kids with type 1 diabetes?
Disease control OngoingThis pilot study is testing whether giving children (ages 6-17) newly diagnosed with stage 3 type 1 diabetes free weekly healthy foods and intensive nutrition counseling can help preserve their remaining insulin production. The study will enroll 20 children and measure how feasib…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Baby shampoo and mouthwash may fight COVID-19, study finds
Disease control OngoingThis study tested whether using a baby shampoo nasal wash and Listerine mouthwash for 4 days could lower the amount of COVID-19 virus in the nose and throat of recently infected adults aged 18-65. Participants were randomly assigned to different wash combinations, including plain…
Phase: PHASE2, PHASE3 • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Bedside ultrasound could speed up DVT diagnosis
Diagnosis ENROLLING_BY_INVITATIONThis study tests whether a fast, bedside ultrasound (called POCUS) can diagnose deep vein thrombosis (DVT) in the leg as accurately as the standard, more time-consuming ultrasound. About 50 adults with DVT symptoms will get both tests, and researchers will compare the results and…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:05 UTC
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New ultrasound technique may spot breast cancer treatment success early
Diagnosis TerminatedThis pilot study aimed to see if contrast-enhanced ultrasound (CEUS) could predict how well triple-negative breast cancer patients respond to chemotherapy and immunotherapy. Researchers planned to measure tumor volume and blood flow changes with CEUS before and during treatment. …
Phase: EARLY_PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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Step up against dementia: fitbit app aims to boost walking in middle age
Prevention ENROLLING_BY_INVITATIONThis study tests whether a smartphone app that sets daily step goals can help middle-aged adults (30-70 years old) who are overweight walk more. Participants use a Fitbit and receive adaptive goals to increase light physical activity. The goal is to see if this simple approach ca…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Prevention
Last updated Jun 27, 2026 12:31 UTC
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Can facing fears help treat anorexia? new study tests exposure therapy
Symptom relief OngoingThis pilot study is testing a new type of exposure therapy for people with anorexia nervosa. The therapy helps patients face their fears about eating and weight gain through real-life and mental exercises. The study involves 30 participants and aims to see if the therapy is feasi…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Can a quick daily workout beat standard group classes for seniors with mobility issues?
Symptom relief OngoingThis study compares two home exercise programs for adults aged 65 and older who have trouble walking. One program (FAST) involves brief daily strength exercises with coaching, while the other (Band Together) is a standard group class done three times a week over Zoom. Researchers…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Soothing sounds may lower surgery jitters in children
Symptom relief OngoingThis study tests whether playing relaxing music through noise-cancelling headphones before surgery can lower stress in children aged 10 to 16 undergoing orthopedic procedures. Researchers will measure changes in heart rate, blood pressure, and breathing rate during anesthesia ind…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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E-Cigarettes may ease COPD symptoms for smokers who switch
Symptom relief OngoingThis early study looks at whether smokers with mild to moderate COPD can improve their symptoms and reduce lung inflammation by switching from regular cigarettes to e-cigarettes. About 30 participants will use e-cigarettes to cut down their smoking by at least 75%. Researchers wi…
Phase: EARLY_PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Hip fracture pain study pulled before it began
Symptom relief TerminatedThis study aimed to see if giving a nerve block before and after hip fracture surgery could reduce pain, confusion, and hospital stays in patients 65 and older. The trial was withdrawn before any participants were enrolled, so no conclusions can be drawn.
Phase: PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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New study uses community events to spark End-of-Life conversations
Knowledge-focused OngoingThis study aims to help people from underserved communities talk about their wishes for end-of-life care and complete advance directives. Researchers will use trusted community networks to host events where two conversation tools are tested. About 1500 adults will participate to …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Radar tech could spot hidden injury risks in soldiers
Knowledge-focused OngoingThis study explores whether micro-Doppler radar, a type of motion-sensing technology, can tell if someone has had ACL knee surgery just by watching how they move. Researchers will compare movement patterns from 181 adults—some with past ACL repairs and some without—while they do …
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Sleep apnea study seeks to uncover hidden heart risks
Knowledge-focused ENROLLING_BY_INVITATIONThis study compares two ways to predict heart and metabolic problems in people with mild-to-moderate obstructive sleep apnea: one based on inflammation in the body, and the other based on how severe the sleep apnea is. Researchers will measure things like waist size, blood pressu…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Study on head position and brain pressure withdrawn before starting
Knowledge-focused TerminatedThis study was designed to see how changing the head position affects pressure inside the skull in people who had a brain bleed from a burst aneurysm. It planned to monitor adults with a pressure monitor already in place. However, the study was withdrawn before enrolling anyone, …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Heart pump showdown: which bypass method protects Kids' organs best?
Knowledge-focused OngoingThis study looks at how two different heart-lung bypass pumps affect the brain, heart, lungs, and kidneys of children during open-heart surgery. One pump sends blood in a steady stream, the other in pulses. About 300 children will take part to see if one method is gentler on vita…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Saliva test may predict teen concussion recovery time
Knowledge-focused OngoingThis study tracks 750 teens aged 13-18 with mild concussions to see if changes in their saliva can predict how long symptoms last. Researchers will check for persistent symptoms 30 days after injury. The goal is to find biological markers that help doctors personalize recovery pl…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Breast Milk's hidden clues: could MicroRNAs predict baby allergies?
Knowledge-focused OngoingThis study followed 221 breastfeeding mothers and their babies to see if small molecules called microRNAs in breast milk are linked to allergies, eczema, or wheezing in the first year of life. Researchers measured these molecules in milk samples and tracked babies' health. The go…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Saliva swab may predict concussion recovery time in kids
Knowledge-focused OngoingThis study is looking at whether changes in RNA found in saliva can help predict how long concussion symptoms will last in children aged 5 to 21. Researchers will collect saliva samples and track symptoms like dizziness and balance problems. The goal is to better understand recov…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Scientists probe why POTS patients feel foggy
Knowledge-focused OngoingThis study looks at why people with Postural Tachycardia Syndrome (POTS) often have trouble thinking clearly, known as 'brain fog.' Researchers will compare brain scans of 21 POTS patients and healthy volunteers while they do mental tasks, both sitting and under simulated standin…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:18 UTC
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Blood and body fluid tests may reveal sepsis risk groups
Knowledge-focused ENROLLING_BY_INVITATIONThis study is measuring certain substances in the blood, stool, saliva, and airway fluid of 200 adults with sepsis. The goal is to see if these biomarkers, combined with standard medical data, can predict which patients are more likely to die or develop long-term critical illness…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:57 UTC