Milton S. Hershey Medical Center
Clinical trials sponsored by Milton S. Hershey Medical Center, explained in plain language.
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Baby shampoo and listerine: surprising weapons against COVID?
Disease control OngoingThis study tests whether using a 4-day routine of nasal washes with diluted baby shampoo and gargling with Listerine can lower the amount of COVID-19 virus in the nose and mouth of recently infected adults aged 18-65. Participants are randomly assigned to different wash combinati…
Phase: PHASE2, PHASE3 • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 17, 2026 04:35 UTC
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Food as medicine: new study tests Diet's power to slow type 1 diabetes in kids
Disease control OngoingThis pilot study tests whether giving children (ages 6-17) with newly diagnosed stage 3 type 1 diabetes free healthy foods and intensive nutrition counseling, alongside standard insulin therapy, can prolong the 'honeymoon phase' and preserve beta cell function. The study enrolls …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Clinic ultrasound could cut DVT diagnosis time
Diagnosis ENROLLING_BY_INVITATIONThis study looks at whether a fast, bedside ultrasound done in a clinic can help diagnose deep vein thrombosis (DVT) more quickly than usual. About 50 adults with DVT symptoms will get this quick ultrasound, followed by a standard confirmatory test. Researchers will compare how f…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Diagnosis
Last updated May 17, 2026 04:36 UTC
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Fitbit app aims to stave off dementia with light walks
Prevention ENROLLING_BY_INVITATIONThis study looks at whether a smart Fitbit app can help middle-aged adults (30–70 years old, overweight) walk more each day. The goal is to see if increasing light physical activity can protect brain health and lower the risk of Alzheimer's and related dementias. Participants use…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Prevention
Last updated May 17, 2026 04:32 UTC
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E-Cigarettes may ease COPD symptoms for smokers
Symptom relief OngoingThis study looks at whether smokers with mild to moderate COPD who switch to e-cigarettes can reduce their symptoms and risk of flare-ups. About 30 participants will use e-cigarettes to cut down on regular cigarettes. Researchers will track lung function, walking distance, and sy…
Phase: EARLY_PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 17, 2026 04:33 UTC
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Soothing tunes may ease kids' pre-surgery jitters
Symptom relief OngoingThis study looks at whether playing calming music to children aged 10 to 16 before orthopedic surgery can lower their stress. Kids wear noise-cancelling headphones playing preselected music from just before anesthesia starts until they are asleep. The researchers measure changes …
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 17, 2026 04:32 UTC
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Can a quick strength routine beat standard exercise for Seniors' mobility?
Symptom relief OngoingThis study tests whether a brief home strength program (FAST) improves leg function more than a standard online exercise class (BAND TOGETHER) in older adults who have trouble walking. About 702 people aged 65 and older with walking difficulty will participate. The goal is to see…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Symptom relief
Last updated May 01, 2026 15:57 UTC
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Sleep apnea study seeks to uncover hidden heart risks
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at 196 adults with mild-to-moderate obstructive sleep apnea to see whether inflammation or the severity of breathing pauses during sleep better predicts heart and metabolic problems. Participants will have their sleep, blood markers, and heart rate variability me…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 04:42 UTC
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Breast milk's hidden clues: tiny molecules linked to baby allergies?
Knowledge-focused OngoingThis study followed 221 breastfeeding mothers and their babies for one year to see if tiny molecules called microRNAs in breast milk are linked to allergies, eczema, or wheezing. Researchers measured these molecules in milk and checked babies for allergic conditions. The goal is …
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 04:38 UTC
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Smartphone app could help ALS patients monitor speech and swallowing
Knowledge-focused OngoingThis study involves 170 people with ALS who will use a smartphone app at home to record their speech and swallowing sounds. The goal is to see if this remote method can accurately track changes in these functions over time. Researchers hope this approach could make monitoring eas…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 04:38 UTC
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Hip fracture pain study pulled before it even started
Knowledge-focused TerminatedThis study planned to test whether a nerve block injection before and after hip fracture surgery could help elderly patients recover better, with less confusion and shorter hospital stays. It was designed for patients aged 65 and older undergoing hip fracture surgery. However, th…
Phase: PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 04:38 UTC
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Scientists hunt for clues in body fluids to outsmart deadly sepsis
Knowledge-focused ENROLLING_BY_INVITATIONThis study is looking for markers in blood, stool, saliva, and lung fluid that can help predict how sepsis will affect a patient. Researchers will combine these markers with standard medical information to identify patients at higher risk of death or long-term illness. The goal i…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 04:36 UTC
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Radar tech spots hidden injury risk in soldiers
Knowledge-focused OngoingThis study tests whether a special radar can tell if someone has had ACL knee surgery by analyzing how they move. Researchers will compare movement data from 181 adults—some with past ACL repair and some without—using radar during simple activities like jumping and walking. The g…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Spit test may forecast concussion recovery time in children
Knowledge-focused OngoingThis study measures tiny molecules in the saliva of 700 children aged 5-21 who had a mild concussion within the past week. Researchers want to see if these molecules can predict how long symptoms like dizziness or trouble thinking will last. No treatment is given; the goal is to …
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Ultrasound may spot breast cancer treatment success early
Knowledge-focused TerminatedThis study aimed to see if contrast-enhanced ultrasound (CEUS) could predict how well triple-negative breast cancer patients respond to chemotherapy and immunotherapy earlier than standard scans. No participants were enrolled, so the study was withdrawn. The goal was to find a fa…
Phase: EARLY_PHASE1 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Study on head position and brain pressure in bleeding patients withdrawn
Knowledge-focused TerminatedThis study was designed to see how changing the head position affects pressure inside the skull in people who had a brain bleed from a burst aneurysm. Researchers planned to monitor patients with special devices to measure brain pressure and blood flow. However, the study was wit…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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Heart pump showdown: does pulsatile flow protect Kids' organs better?
Knowledge-focused OngoingThis study looks at how two different heart-lung bypass pumps affect the brain, heart, lungs, and kidneys of 300 children during open-heart surgery. One pump sends blood in a steady stream, while the other sends it in pulses like a natural heartbeat. The goal is to see if one met…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:51 UTC
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Wearable sensors track ALS progression from home
Knowledge-focused OngoingThis study tests whether wearable sensors and digital tasks can help monitor motor function in people with ALS, PLS, or PMA. Twenty participants wear neck and wrist sensors during daily activities and complete speech, handwriting, and tracing tasks at home and in clinic over 48 w…
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:47 UTC
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Scientists scan brains to unravel the mystery of POTS 'Brain Fog'
Knowledge-focused OngoingThis study aims to understand why people with Postural Tachycardia Syndrome (POTS) experience 'brain fog'—difficulty with thinking and memory. Researchers will use brain scans to compare brain activity in 21 people with POTS to healthy volunteers while they do thinking tasks. The…
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated May 08, 2026 12:04 UTC
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Saliva test may predict teen concussion recovery time
Knowledge-focused OngoingThis study aims to find out if certain molecules in saliva can predict how long concussion symptoms last in teenagers aged 13-18. Researchers will track 750 teens with mild concussions and check their symptoms after 30 days. The goal is to better understand recovery patterns and …
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:01 UTC