Scientists probe why POTS patients feel foggy
NCT ID NCT04137757
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looks at why people with Postural Tachycardia Syndrome (POTS) often have trouble thinking clearly, known as 'brain fog.' Researchers will compare brain scans of 21 POTS patients and healthy volunteers while they do mental tasks, both sitting and under simulated standing stress. The goal is to see if brain regions work harder in POTS patients, especially when upright.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help explain the cause of brain fog in POTS, pointing toward future treatments or management strategies.
What could go wrong
This is a small, early-stage observational study with only 21 participants. It is not testing a treatment, so it may not lead directly to any therapy.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for POSTURAL TACHYCARDIA SYNDROME are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Penn State Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033, United States