Ku Leuven

This study tests whether a home-based breathing exercise program can reduce hospital readmissions and deaths in people recovering from a severe COPD flare-up. About 358 participants will either receive usual care or add daily inspiratory muscle training using a smartphone-connect…

This study tests a digital tool that gives doctors real-time, guideline-based advice on prescribing antibiotics. About 48 general practices in Belgium will use the tool during patient visits. The goal is to see if it reduces unnecessary antibiotic use and helps fight antibiotic r…

This study tests whether a coordinated care program called I-CONNECT can improve the health and well-being of older adults (65+) who have depression or bipolar disorder and at least two chronic physical conditions like diabetes or high blood pressure. Participants receive persona…

This study aims to improve how doctors tell the difference between borderline ovarian tumors and early-stage invasive ovarian cancer before surgery. Researchers will test a panel of nine blood-based biomarkers in 400 women with suspicious ovarian cysts. If successful, this could …

This study is testing a smartphone app that lets rectal cancer patients log their bowel symptoms daily. The goal is to create a better tool for doctors to understand and manage these symptoms. About 158 participants who had rectal surgery or are on a watch-and-wait plan will use …

This study tests a new, quick blood test done right in the emergency room to rule out heart attacks in people with chest pain. The goal is to see if this faster test can get patients discharged sooner compared to the usual lab test, which can take an hour or more. About 1,500 adu…

This study aims to see if certain chemicals (oncometabolites) in a person's breath and blood can spot early-stage gastro-esophageal cancer. Researchers will compare samples from 1,000 people, including those with cancer, those with Barrett's esophagus (a precancerous condition), …

This study looks at whether doing a 12-week exercise program with your feet turned outward (toes-out) helps people with mid-portion Achilles tendinopathy more than the usual neutral-foot position. About 60 adults aged 18–65 with Achilles pain will be followed for 6 months. Resear…

This small study in Uganda looks at how meals made with local fruits and vegetables affect blood sugar and fat levels in people with type 2 diabetes. Eight participants will eat five different test meals over five weeks, with blood samples taken over three hours after each meal. …

This phase 2 trial tests whether taking CBD before bed can improve sleep quality after a late evening high-intensity workout. Twenty healthy adults will each complete a rest session and two exercise sessions, receiving either CBD or a placebo. Sleep is measured overnight using br…

This study tests whether using a fluid enriched with hyaluronan (a natural substance) during embryo transfer can help more women achieve a lasting pregnancy. About 400 women under 40 who have not had a successful pregnancy after previous IVF attempts will take part. The main goal…

This study tests whether adding one hour of arm-hand exercises daily (5 days a week for 4 weeks) to usual care helps stroke patients regain arm function. 80 people who had a stroke within the last 5 months will be randomly assigned to either the extra arm-hand program or a lower-…

This study looks at whether inhaling menthol can quickly relieve shortness of breath in healthy adults and people with COPD. Researchers will measure brain activity and breathing to understand how menthol works. The goal is to find a simple, drug-free way to ease breathing discom…

This study tests a multidisciplinary rehab program (Revita) for people with long-term low back pain or spine problems. The program combines physical therapy with psychological, social, or educational support over up to 36 sessions. Researchers will measure changes in disability, …

This study tests an artificial intelligence algorithm that uses wearable sensors to detect freezing of gait—a sudden inability to walk—in people with Parkinson's disease. Researchers want to see if the AI works accurately in home environments, not just in the lab. About 126 parti…

This study is testing a machine learning model that uses past lung function tests to predict future changes in 4,000 adults with chronic respiratory diseases. Researchers will check if the model's predictions match real outcomes like hospital visits and health status. The goal is…

This study takes small tissue samples from the rectum of people with irritable bowel syndrome (IBS) and healthy volunteers to measure how the nerves in the gut are working. Researchers will use special imaging and other lab techniques to see how these nerves respond to different …

This study looks at how different types of breathing muscle training affect patients in the ICU who are having trouble coming off a ventilator. Researchers will compare usual care with two forms of inspiratory muscle training (one high-intensity, one low-intensity) in 90 adults. …

This study tests two ways of cycling while lying in a hospital bed for patients in the intensive care unit (ICU). One method is steady cycling for 10-20 minutes, and the other is short bursts of harder cycling mixed with easier pedaling. The goal is to see which approach better a…

This study uses a 20-25 minute survey to find out which features of diagnostic tests for gastro-esophageal cancer matter most to patients and the general public. Researchers aim to understand preferences and regional differences to improve screening decisions. About 2,200 adults …

After a stroke, many people struggle to use both hands together. This study checks if a new test called the Ad-AHA Stroke accurately measures how people actually use their hands in daily life. Thirty-two stroke survivors will wear wrist sensors for three days while their hand use…

This study follows 150 rectal cancer patients to understand why some have long-term bowel problems after treatment. Participants use a smartphone app to track symptoms and fill out quality-of-life questionnaires. The goal is to create personalized care plans that address each pat…

This study looks at different forms of IgE (a protein involved in allergic reactions) in healthy volunteers and people with conditions like severe allergies, chronic hives, mastocytosis, and immune deficiencies. Researchers aim to understand how these IgE variations relate to hea…

This study checks if a new smartphone-based method called ESDAM can accurately measure daily food and drink intake. Researchers will compare ESDAM results with objective lab tests in 115 healthy adults. The goal is to see if this app can be a reliable tool for future nutrition re…