Istituto Ortopedico Rizzoli

This study tested whether injecting a patient's own fat-derived cells (stromal vascular fraction) into the damaged knee tendon could improve symptoms and function in patellar tendinopathy. Thirty adults with tendon damage seen on imaging were treated. The goal was to control the …

This study tested a new material called OrthoPure XT for repairing torn knee ligaments (ACL) in 10 people. Researchers measured pain, knee function, and healing using MRI scans. The goal was to see if this material works well for patients who cannot use their own tissue for the r…

This study looked at two types of surgery for teens with scoliosis (a curved spine): vertebral body tethering (VBT) and posterior spinal fusion (PSF). The goal was to see which one corrects the curve better and keeps the spine flexible for movement. Researchers followed 12 teens …

This pilot study tested a mini-invasive spine surgery in one person with neuromuscular scoliosis, a severe spine curve caused by nerve or muscle problems. The goal was to see if the less invasive approach could safely correct the spine curve and reduce pain. The study was complet…

This study tested an ultrasound-guided injection of a steroid and numbing medicine into the knee for people with medial plica syndrome that did not get better with other treatments. 30 adults received the injection plus physical therapy. The goal was to see if the treatment reduc…

This study tested whether a special nerve block (ESP block) given before spinal surgery could lower pain and reduce the need for strong painkillers in teens with scoliosis. Eleven adolescents took part, with half receiving the block plus general anesthesia and half receiving only…

This study tested a new treatment for hip osteoarthritis using a person's own fat tissue. Doctors took a small amount of fat, broke it up to release stem cells, and injected it into the painful hip joint. The goal was to see if it was safe and could reduce pain and improve moveme…

This study tested a treatment for a condition called superior cluneal nerve entrapment, where a nerve in the lower back gets pinched and causes pain. 41 adults with this type of nerve pain received injections to relieve the pressure. The goal was to see if this approach could red…

This study tested whether combining a 5-day sailing therapy program with a 3-month home telerehabilitation plan is safe and doable for 24 young people (ages 12–30) with rare skeletal disorders. Participants were randomly assigned to either the sailing-plus-telerehab group or a te…

This study looked at how people with spinal tumors move before and after a surgery called vertebrectomy. Ten adults had their walking, standing, and trunk movements analyzed with special motion-capture technology. The goal was to better understand how surgery changes movement, wh…

This study looked at whether simple balance and movement tests can predict which patients are likely to fall after hip or knee replacement surgery. Researchers tested 200 patients before their operation using tools like the Timed Up and Go test and a step test. They then tracked …

This study looked at tumor samples from 80 people with localized osteosarcoma who had already received chemotherapy with or without a drug called mifamurtide. Researchers analyzed 770 genes related to the immune system to see how the tumor's environment affects survival. The goal…

This study looked at 60 healthy volunteers aged 18 to 35 to measure the normal temperature of the knee using a special heat-sensing camera. The goal was to create a set of standard temperature values for different parts of the knee and see if gender or physical activity changes t…

This study looked at 107 patients who had surgery for a broken ankle bone (the fibula) to see how well they recovered. Researchers checked medical records and X-rays to track bone healing and asked patients to fill out questionnaires about their function and pain one year after s…

This study looked at whether common conditions like flat feet, knock knees, or scoliosis affect how children move and control their bodies. Researchers used wearable motion sensors and simple tests to compare 151 children with these conditions to healthy kids of the same age. The…

This study looked at 42 people who had surgery for multiple torn knee ligaments, often from high-energy accidents. Researchers measured knee function and symptoms using standard scores to see how well patients did over the long term. The goal was to gather information to help doc…

This study looked at DNA methylation patterns in stored samples from 90 patients with rare skeletal disorders, sarcomas, or inflammatory arthritis. The goal was to better understand these diseases and improve how biobank data is shared for future research. No new treatments were …

This study followed 100 cancer patients who had surgery to remove and rebuild part of their lower leg or pelvis. Researchers measured how independent they became in daily activities and how much joint movement they regained over the first 6 months. The goal was simply to describe…

This study followed 41 people who had a scaffold implanted to treat partial meniscus tears in the knee. Researchers collected data from medical records and phone interviews to see how patients' pain, knee function, and quality of life changed over time. The goal was to understand…

This study looked at 30 adults who completely tore their distal biceps tendon and chose not to have surgery. Researchers measured elbow function, arm strength, and fatigue after at least one year, comparing the injured arm to the healthy one. The goal was to see if conservative (…