Istituto Ortopedico Rizzoli

This pilot study tested a surgical technique using donor tissue without metal implants to treat recurrent shoulder dislocation with bone loss. Twenty participants were followed for 24 months to measure arm function and safety. The goal was to see if this approach can stabilize th…

This study looked at two types of surgery for teens with scoliosis (a curved spine). One method, called vertebral body tethering (VBT), uses a flexible cord to straighten the spine while allowing more natural movement. The other, posterior spinal fusion (PSF), permanently fuses t…

This study tested an injection of stromal vascular fraction, a mixture of cells from the patient's own fat tissue, for patellar tendinopathy (jumper's knee). Thirty participants received the injection under ultrasound guidance. The goal was to see if it could improve symptoms and…

This study tested a new material called OrthoPure XT for repairing torn anterior cruciate ligaments (ACL) in the knee. Ten patients received the graft and were followed with questionnaires and MRI scans to assess knee function, pain, and healing. The goal was to see if OrthoPure …

This study tested whether GPT-4, an AI language model, can diagnose and recommend treatments for failed hip replacements as well as human surgeons. Researchers presented 20 anonymized patient cases to GPT-4 and three surgeons with different experience levels. The goal is to see i…

This study looked at tiny molecules in the blood, called microRNAs, to see if they can help diagnose adolescent idiopathic scoliosis (AIS), a condition that causes a curved spine in teens. Researchers compared blood samples from 20 teens with AIS and 10 healthy teens to find diff…

This study tested whether a 6-month adapted physical activity program could improve functional capacity in people with hemophilia. Fourteen participants did exercises twice a week to improve joint mobility, strength, and balance. The main goal was to see if their walking distance…

This pilot study tested whether a 5-day sailing therapy program followed by 3 months of home-based telerehabilitation is safe and feasible for young people aged 12–30 with rare skeletal disorders. 24 participants were randomly assigned to either the sailing-plus-rehab group or a …

This study tested a less invasive spine surgery in one person with neuromuscular scoliosis, a severe spine curve caused by nerve or muscle problems. The goal was to see if the mini-invasive approach could reduce pain, blood loss, and complications compared to standard surgery. Th…

This study tested whether injecting a patient's own processed fat tissue into the arthritic hip joint could safely reduce pain and improve movement. Thirty adults with mild to moderate hip osteoarthritis received one ultrasound-guided injection. Researchers measured changes in pa…

This study tested a steroid injection into a trapped nerve in the lower back to see if it reduces pain and improves daily activities. 41 adults with low back pain from superior cluneal nerve entrapment received the injection. The goal was to measure pain levels and disability bef…

This study tested whether an ultrasound-guided nerve block (ESP block) given before spinal surgery for scoliosis can lower pain and the need for strong painkillers after the operation. Eleven teenagers took part, with half receiving the block plus general anesthesia and half rece…

This pilot study tested an ultrasound-guided injection of triamcinolone (a steroid) mixed with lidocaine (a numbing agent) directly into the knee's medial plica fold. The goal was to see if this targeted approach could reduce pain and improve function in 30 people with medial pli…

This completed study reviewed data from 31 patients who had knee replacement revision surgery due to aseptic loosening (the implant coming loose without infection). Researchers used a regional registry and X-ray analysis to understand the causes and economic impact. The goal was …

This completed study enrolled 33 people with osteogenesis imperfecta (OI), a condition that makes bones fragile. Researchers used special sensors and gait analysis to measure how participants move. The goal was to identify which movement patterns are most useful for understanding…

This study looked at DNA methylation patterns in stored samples from 90 patients with rare skeletal disorders, sarcomas, or inflammatory arthritis. The goal was to better understand these patterns and explore their potential for diagnosis and treatment. The research aimed to impr…

This completed study looked at 60 healthy volunteers aged 18 to 35 to measure the normal temperature of different parts of the knee using a special camera (thermography). The goal was to create a set of reference values for knee temperature and to see if gender or physical activi…

This study looks at how well people recover from a complete tear of the distal biceps tendon without surgery. Researchers followed 30 patients for at least one year, measuring elbow function, strength, and fatigue. The goal is to see if conservative (non-surgical) treatment can b…

This study looked at 42 people who had surgery for multiple torn knee ligaments between 2000 and 2019. Researchers measured knee function and symptoms using standard questionnaires. The goal was to understand how well surgery works for these serious injuries, which can cause long…

This study looked at 200 patients who had hip or knee replacement surgery. Researchers used simple tests like standing on a platform and timed walking to see if they could predict who might fall during recovery. The goal was to find better ways to identify fall risk and help pati…

This study reviewed medical records of 107 patients who had surgery for a broken ankle (distal fibula fracture) using metal plates. Researchers looked at X-rays to see when the bone healed and asked patients about their function and pain one year after surgery. The goal was to be…

This study followed 100 people who had surgery to remove bone or soft tissue tumors in their leg or pelvis. Researchers measured how independent they became in daily activities and how well their joints moved during the first six months after surgery. The goal was simply to descr…

This study looked at how the spine moves in 10 people with spinal tumors before and after vertebrectomy surgery. Researchers used motion analysis to measure walking, standing, and trunk movements. The goal was to better understand spine function and possibly improve future treatm…

This study followed 41 patients who received a scaffold implant for partial meniscal tears in the knee. Researchers collected data from telephone surveys and medical records to see how well patients were doing over time. The goal was to understand if this treatment helps with pai…

This completed study looked at 151 children with common postural conditions like flat feet, knock knees, or scoliosis. Researchers used wearable motion sensors and clinical tests to measure balance and motor control, then compared the results to healthy children. The goal was to …

This study examined stored tumor samples from 80 people with localized osteosarcoma who received chemotherapy with or without the drug mifamurtide. Researchers analyzed the immune cells and genes inside the tumors to see how the tumor environment relates to patient survival. The …