Scientists probe tumor immune cells in bone cancer patients treated with mifamurtide

NCT ID NCT03737435

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study examined stored tumor samples from 80 people with localized osteosarcoma who received chemotherapy with or without the drug mifamurtide. Researchers analyzed the immune cells and genes inside the tumors to see how the tumor environment relates to patient survival. The goal is to better understand why some patients respond better to treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mifamurtide

What this could lead to

If successful, this could help doctors understand which patients with osteosarcoma might benefit most from adding mifamurtide to chemotherapy.

What could go wrong

This is a retrospective biological study, not a treatment trial. It only looks at stored tumor samples, so it cannot prove that mifamurtide works better or causes harm.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

localized osteosarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • SSD Chemioterapia dei tumori dell'apparato locomotore

    Bologna, 40136, Italy