Needle precision: ultrasound-guided shot eases stubborn knee pain

NCT ID NCT04943341

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested an ultrasound-guided injection of triamcinolone (a steroid) mixed with lidocaine (a numbing agent) directly into the knee's medial plica fold. The goal was to see if this targeted approach could reduce pain and improve function in 30 people with medial plica syndrome who hadn't improved with standard treatments. Researchers tracked outcomes using pain scales and knee function scores, along with safety monitoring.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Triamcinolone Acetonide (Kenacort) with Lidocaine

What this could lead to

If it works, this could offer a targeted, non-surgical option for persistent knee pain from medial plica syndrome.

What could go wrong

This is a small pilot study with only 30 people, so results may not apply widely. The injection is a steroid, which can have side effects like tissue damage or infection, though rare.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

synovial plica syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Istituto Ortopedico Rizzoli

    Bologna, 40136, Italy