New ACL graft shows promise in tiny trial
NCT ID NCT06091488
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a new material called OrthoPure XT for repairing torn anterior cruciate ligaments (ACL) in the knee. Ten patients received the graft and were followed with questionnaires and MRI scans to assess knee function, pain, and healing. The goal was to see if OrthoPure XT is a safe and effective option when other graft types cannot be used.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
OrthoPure XT (a graft material for knee ligament reconstruction)
What this could lead to
If successful, OrthoPure XT could offer a reliable option for ACL reconstruction when other graft sources are not suitable.
What could go wrong
This was a very small study (10 people) with no comparison group, so results may not apply broadly. Long-term safety and effectiveness are not yet established.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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IRCCS Istituto Ortopedico Rizzoli
Bologna, 40136, Italy