Stem cell byproduct may boost ACL graft healing — trial puts it to the test

This trial tests whether adding a single injection of MSC-derived secretome — a substance produced by stem cells — during ACL reconstruction surgery can improve knee function and recovery. Twenty-four adults with a complete ACL tear will receive either the secretome or a placebo, and their knee function will be measured before surgery and six months later using standard knee scores. The goal is to see if the secretome helps the graft heal better and leads to a faster, more complete recovery.