ACL INJURY
Clinical trials for ACL INJURY explained in plain language.
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Could an asthma drug shield knees from arthritis after ACL surgery?
Disease control Recruiting nowThis trial investigates whether montelukast, a common asthma medication, can reduce inflammation and prevent cartilage breakdown after anterior cruciate ligament (ACL) reconstruction. The study enrolls adults aged 25 to 50 who also have a meniscus tear, a group at high risk for r…
Matched conditions: ACL INJURY
Phase: EARLY_PHASE1 • Sponsor: Austin V Stone • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Could an extra stitch save Kids' ACL repairs? new trial aims to find out
Disease control Recruiting nowThis study is testing whether repairing an additional knee ligament (the ALL) at the same time as standard ACL surgery can lower the chance of the ACL graft failing in children. About 240 kids aged 18 and under who need ACL surgery will be randomly assigned to get either the stan…
Matched conditions: ACL INJURY
Phase: NA • Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New surgery aims to fix partial ACL tears without full reconstruction
Disease control Recruiting nowThis study tests a surgery called ACL augmentation for people with a partial tear of the anterior cruciate ligament (ACL) in the knee. The goal is to improve knee function and stability. The study will enroll 30 participants aged 15 to 50 who have a partial ACL tear and no other …
Matched conditions: ACL INJURY
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Could a bone marrow shot stop arthritis after ACL surgery?
Disease control Recruiting nowThis study tests whether a concentrated bone marrow injection (cBMA) given during repeat ACL surgery can reduce knee pain and signs of arthritis. About 40 adults aged 18-55 who need a second ACL repair will receive either cBMA plus surgery or surgery alone. Researchers will track…
Matched conditions: ACL INJURY
Phase: PHASE4 • Sponsor: Hospital for Special Surgery, New York • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Skip the knife? new study tests rehab-only for ACL tears
Disease control Recruiting nowThis study looks at whether people with an ACL knee injury can get better with rehabilitation alone, without surgery. Researchers will track 400 participants to see how their knee functions and how many end up needing surgery. The goal is to find out if non-surgical treatment is …
Matched conditions: ACL INJURY
Sponsor: Aarhus University Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Special treadmill training may help ACL recovery
Symptom relief Recruiting nowThis study tests whether walking on a split-belt treadmill (where each leg moves at a different speed) can improve how the knee loads weight after ACL reconstruction. Nine people who had ACL surgery within the past 10 months will be randomly assigned to one of two training groups…
Matched conditions: ACL INJURY
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 26, 2026 14:59 UTC
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Calf muscle strength under scrutiny in ACL injury study
Knowledge-focused Recruiting nowThis study looks at whether people with a torn ACL have weakness in the soleus, a calf muscle that helps protect the knee. Researchers will test leg strength in 55 participants with ACL tears and compare them to healthy individuals. The goal is to better understand muscle changes…
Matched conditions: ACL INJURY
Sponsor: University of Liverpool • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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5,000 athletes to help unlock secrets of ACL injuries
Knowledge-focused Recruiting nowThis observational study will collect movement data from 5,000 healthy athletes aged 10 to 65 who play organized sports. Researchers will track participants for 12 months to see who gets injured, especially ACL tears. The goal is to build a database of normal movement patterns to…
Matched conditions: ACL INJURY
Sponsor: Sanford Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Brain scans reveal how ACL rehab rewires the mind to prevent Re-Injury
Knowledge-focused Recruiting nowThis study looks at 12 people who had ACL knee surgery to see if a special exercise program (neuromotor training) can change how their brain controls movement. Participants will get brain scans (fMRI) before and after the training. The goal is to understand if this training helps…
Matched conditions: ACL INJURY
Phase: NA • Sponsor: Stefano Zaffagnini • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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ACL surgery under the microscope: 5-Year study tracks recovery
Knowledge-focused Recruiting nowThis study follows 1000 patients who have ACL reconstruction surgery to see how their knees hold up over time. Researchers check knee stability and quality of life before surgery and at 6 months, 1, 2, and 5 years after. The goal is to better understand long-term recovery and fun…
Matched conditions: ACL INJURY
Sponsor: Stefano Zaffagnini • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Smart sock could help athletes know when They're ready to play again
Knowledge-focused Recruiting nowThis study is testing a wearable sensor that measures muscle oxygen levels in high school and college athletes recovering from ACL or hip surgery. The goal is to see if the sensor can give doctors and trainers better data to decide when an athlete is ready to return to sports. Ab…
Matched conditions: ACL INJURY
Phase: NA • Sponsor: University Hospitals Cleveland Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC