ACL INJURY

This trial tests whether adding a single injection of MSC-derived secretome — a substance produced by stem cells — during ACL reconstruction surgery can improve knee function and recovery. Twenty-four adults with a complete ACL tear will receive either the secretome or a placebo,…

This trial tests whether adding a special bone-like scaffold to the standard hamstring tendon graft improves healing after ACL reconstruction. The scaffold is designed to help the graft bond better with the bone and reduce bone tunnel widening. About 56 people with a recent ACL t…

This study investigates whether a single session of whole-body vibration can improve how people with a history of anterior cruciate ligament (ACL) reconstruction land from a jump. Poor landing mechanics are linked to a higher risk of re-injury. Participants stand on a vibrating p…

This study compared two rehab approaches after ACL reconstruction: Blood Flow Restriction (BFR) training alone versus BFR combined with Total Motion Release (TMR). 44 participants aged 16-45 did supervised sessions three times a week for six months. The goal was to see if adding …

This study tested a new material called OrthoPure XT for repairing torn anterior cruciate ligaments (ACL) in the knee. Ten patients received the graft and were followed with questionnaires and MRI scans to assess knee function, pain, and healing. The goal was to see if OrthoPure …

This study tested a new MRI technique called diffusion tractography to better diagnose partial tears of the anterior cruciate ligament (ACL) in the knee. Standard MRI often cannot tell how severe a partial tear is, making treatment decisions difficult. Researchers enrolled 30 adu…

This study tested a new scale called SHD-LESS to see if it can detect landing asymmetry in people who had ACL reconstruction surgery. Sixty participants performed a single hop for distance while being recorded on video, and two doctors scored their landing technique. The goal is …

This study tested whether adding blood flow restriction (BFR) therapy to standard physical rehabilitation helps people recover better after anterior cruciate ligament (ACL) knee surgery. Sixty active-duty military members and their families, aged 15 to 45, were randomly assigned …

This study looked at 54 young male football players who had ACL surgery using either a quadriceps tendon graft or a semitendinosus tendon graft. The goal was to see which method leads to better leg strength and a higher rate of returning to sports within two years. The results he…

This study tested whether walking on a treadmill with belts moving at different speeds can improve how the knee loads weight after ACL reconstruction. Thirty-two participants who had ACL surgery within the past 10 months walked on the treadmill for 20 minutes. Researchers measure…