Could a Parent's hamstring tendon rebuild a Child's torn ACL?

NCT ID NCT05395767

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial is testing whether using a hamstring tendon from a parent can safely and effectively reconstruct a torn anterior cruciate ligament (ACL) in children and teenagers whose bones are still growing. The study will enroll 40 patients aged 8 to 17 with ACL tears that need surgery. The parent donates one of their hamstring tendons, which is then implanted into the child during arthroscopic knee surgery. Researchers will track knee function, symptoms, and ability to return to sports for up to two years after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
living donor hamstring allograft from a parent
What this could lead to
If successful, this approach could offer children with ACL tears a reliable graft option that avoids the risks of using their own tissue.
What could go wrong
This is a small, early-stage study with only 40 participants. The donor surgery carries its own risks, and long-term outcomes are not yet known.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Trauma & Orthopaedic Dept, Tunbridge Wells Hospital

    RECRUITING

    Pembury, Kent, TN2 4QJ, United Kingdom

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