Knee replacement failures under the microscope: new study analyzes costs and X-Rays

NCT ID NCT06821581

Completed Knowledge-focused Sponsor: Istituto Ortopedico Rizzoli Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study reviewed data from 31 patients who had knee replacement revision surgery due to aseptic loosening (the implant coming loose without infection). Researchers used a regional registry and X-ray analysis to understand the causes and economic impact. The goal was to identify patterns that could help improve future surgeries and reduce healthcare costs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help healthcare systems better predict and manage knee replacement failures, potentially reducing costs and improving patient outcomes.
What could go wrong: This is a small, completed observational study with only 31 patients. It does not test a new treatment, so it cannot directly improve care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHROPATHY OF KNEE ASEPTIC LOOSENING

Contacts and locations

Locations

IRCCS Istituto Ortopedico Rizzoli

Bologna, Bologna, 40136, Italy

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