Indiana University
Clinical trials sponsored by Indiana University, explained in plain language.
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Magic mushroom therapy tested for Veterans' depression and addiction
Disease control Not yet recruitingThis study is testing whether a single dose of psilocybin (the active compound in 'magic mushrooms'), given alongside supportive psychotherapy, is safe and can help reduce symptoms of depression and substance use. It will involve 50 veterans and first responders who have not resp…
Phase: PHASE1, PHASE2 • Sponsor: Indiana University • Aim: Disease control
Last updated Apr 01, 2026 23:26 UTC
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Online therapy trial aims to stop a hidden health threat in HIV
Disease control Not yet recruitingThis study is testing if treating depression can help prevent a worsening of insulin resistance, a condition that can lead to diabetes, in adults with HIV. Researchers will compare a 9-week online cognitive behavioral therapy program to an educational program about depression. Th…
Phase: NA • Sponsor: Indiana University • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Race against time: finding the perfect polyp checkup schedule
Disease control Not yet recruitingThis study aims to determine whether checking for polyp regrowth at 6 months or 12 months after removal is better for patient safety and convenience. Researchers will follow 546 adults who had large, non-cancerous colon polyps removed to see which follow-up schedule best catches …
Phase: NA • Sponsor: Indiana University • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New study tests Low-Cost autism support for families worldwide
Disease control Not yet recruitingThis study aims to test two ways to train caregivers of children with autism to improve family well-being and child communication. It will compare programs led by professionals versus those led by other trained caregivers in Kenya, with lessons applied to a pilot program in the U…
Phase: NA • Sponsor: Indiana University • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Pedaling in bed: new device aims to fight hospital weakness
Disease control Not yet recruitingThis study is testing a simple exercise bike that attaches to a hospital bed. The goal is to see if patients can safely use it to stay active during their stay, which may help prevent common problems like muscle loss, blood clots, and confusion. Researchers will enroll 80 adult p…
Phase: NA • Sponsor: Indiana University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Hormone supplement trial aims to help asthma patients
Disease control Not yet recruitingThis study is testing whether a slow-release version of the hormone supplement DHEA can help adults with asthma who already use steroid inhalers. Researchers want to see if adding DHEA improves asthma control and is safe, since standard asthma steroids can lower the body's natura…
Phase: PHASE2 • Sponsor: Indiana University • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Can extra coaching stop diabetes in pregnancy?
Prevention Not yet recruitingThis study aims to see if a more intensive diet and exercise counseling program can help prevent gestational diabetes in high-risk pregnant people, compared to the standard counseling they usually receive. It will enroll 100 participants who are at higher risk due to factors like…
Phase: NA • Sponsor: Indiana University • Aim: Prevention
Last updated Mar 25, 2026 14:08 UTC
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Kenyan project aims to stop cervical cancer before it starts
Prevention Not yet recruitingThis project continues a community effort in rural Kenya to prevent cervical cancer. It aims to vaccinate 2000 girls against HPV and screen 500 women, while also studying what prevents families from joining such health programs. The goal is to understand how to best deliver cance…
Phase: NA • Sponsor: Indiana University • Aim: Prevention
Last updated Mar 23, 2026 15:19 UTC
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New bedside monitor aims to soothe sleepless nights for dementia patients
Symptom relief Not yet recruitingThis study is testing whether a non-contact sleep monitor can help improve sleep for people with Alzheimer's living in long-term care. For 100 participants, the monitor will track sleep for four weeks. Researchers want to see if sharing this sleep data with care staff leads to be…
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Zapping the ear to calm the stomach: new hope for diabetes patients
Symptom relief Not yet recruitingThis study is testing whether a small device that gently stimulates nerves near the ear can help reduce nausea, vomiting, and other stomach symptoms in people with diabetes. Researchers want to see if this stimulation affects the 'vagus nerve,' which controls stomach function. Ab…
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Suction device could revolutionize IUD placement pain
Symptom relief Not yet recruitingThis study compares two methods for holding the cervix steady during IUD insertion: a new suction device versus the standard clamp. Researchers want to see if the suction device causes less pain for patients and is easier for doctors to use. About 100 women getting IUDs will be r…
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Can hospital chaplains ease the agony for ICU families?
Symptom relief Not yet recruitingThis study is testing whether a special chaplain-led support program can help family members who are making medical decisions for a critically ill loved one in the ICU. It aims to reduce their anxiety and improve their spiritual well-being during this stressful time. The program …
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Can a playlist get kids moving? study tests Music's power in PE class
Symptom relief Not yet recruitingThis study aims to see if playing upbeat music during a school sports program makes kids more active and enjoy exercise more. About 35 fifth and sixth graders will participate in an 8-week program, with some classes having music and others not. Researchers will track steps and as…
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Mar 25, 2026 14:09 UTC
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Step into recovery: VR headsets aim to rebuild walking after brain injury
Symptom relief Not yet recruitingThis study is testing a new virtual reality (VR) program to help people with traumatic brain injury or stroke improve their walking. It compares immersive VR therapy where patients walk on the ground to a standard treadmill-based VR system. The goal is to see if the immersive VR …
Phase: NA • Sponsor: Indiana University • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Eye drop showdown: which works better for dry eyes?
Symptom relief Not yet recruitingThis study compares two eye drop treatments for dry eye disease to see if they work equally well at relieving symptoms. Researchers will enroll 260 adults with moderate dry eye and randomly assign them to use either SYSTANE PRO or MIEBO drops for one month. The main goal is to se…
Phase: PHASE4 • Sponsor: Indiana University • Aim: Symptom relief
Last updated Mar 23, 2026 15:19 UTC
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Better charts for twins: study tests new way to track baby growth
Knowledge-focused Not yet recruitingThis study aims to find out if using growth charts specifically designed for twins leads to better care than using standard pregnancy charts. Researchers will randomly assign 150 pregnant people carrying twins to have their care guided by either traditional charts or twin-specifi…
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Apr 01, 2026 23:26 UTC
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Blood test trial aims to spot lingering cancer
Knowledge-focused Not yet recruitingThis study aims to see if a blood test can find tiny bits of leftover cancer after treatment for testicular and related cancers (germ cell tumors). Researchers will collect blood samples from 130 adults with early to advanced-stage cancer to see how well the test predicts if canc…
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Blood holds clues to cancer treatment success
Knowledge-focused Not yet recruitingThis study aims to find markers in the blood that can predict how well a cancer patient will respond to immunotherapy and what side effects they might experience. Researchers will collect blood samples from 100 adults with cancer who are starting immunotherapy treatment. The goal…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Can a phone app fight burnout and improve therapy?
Knowledge-focused Not yet recruitingThis study is testing a new smartphone app called SuperAssist, designed to help mental health providers and their supervisors work together better. Researchers will enroll 180 providers and some of their clients to see if using the app for six months improves job satisfaction, re…
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:10 UTC
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Can swapping burgers for beans help kidneys?
Knowledge-focused Not yet recruitingThis study aims to understand how replacing red meat with plant-based proteins affects gut health and toxin levels in people with moderate kidney disease. Fifteen participants will try two different diets for several weeks each while researchers measure blood and urine markers. T…
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Scientists test if extreme temps make hard breathing even worse for thinking
Knowledge-focused Not yet recruitingThis study aims to understand how breathing difficulty and thinking skills are affected when people breathe against resistance in hot or cold environments. It will enroll 15 healthy, fit adults who will breathe through a restrictive device while being exposed to controlled temper…
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Scientists search for Autism's earliest clues in Mothers' blood
Knowledge-focused Not yet recruitingThis study aims to find early signs that might predict if a child will develop autism. Researchers will look at blood and urine samples collected from 600 first-time mothers during pregnancy. They will use this information to try to build a model that could one day help identify …
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Massive US study seeks to uncover why millions have sensitive teeth
Knowledge-focused Not yet recruitingThis study aims to understand how common tooth wear and tooth sensitivity are among adults across the United States. Researchers will examine 2,500 people at dental schools in five different regions to look for links between these conditions and people's habits, health, and backg…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Can music help soldiers breathe and think better under pressure?
Knowledge-focused Not yet recruitingThis study aims to understand if changing what people hear while breathing against resistance can help them feel less breathless and think more clearly. It will test healthy, active adults by having them breathe through a device that makes breathing harder while listening to norm…
Phase: NA • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:09 UTC
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Cancer treatment side effects linked to drug Mix-Ups?
Knowledge-focused Not yet recruitingThis study aims to understand why cancer immunotherapy drugs sometimes cause serious side effects. Researchers suspect these drugs might change how the liver processes other medications patients are taking. The study will give 80 cancer patients a special cocktail of safe test dr…
Phase: EARLY_PHASE1 • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC
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New scan aims to predict cancer treatment success
Knowledge-focused Not yet recruitingThis study is testing a new type of PET scan to see if it can help doctors better predict how patients with advanced head and neck cancer will respond to standard chemoradiation treatment. It will involve 5 patients who are scheduled for this standard treatment. The goal is to le…
Phase: EARLY_PHASE1 • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC