Indiana University

This study compares two common techniques doctors use to remove colon polyps during routine colonoscopies. Researchers want to know which method—cold snare piecemeal resection or cold endoscopic mucosal resection—is more effective at completely removing polyps that could turn int…

This study is testing whether two different types of telemedicine (remote doctor visits) can help children with sickle cell disease get better care when they live far from specialty clinics. Researchers are working with 24 families to see if virtual visits improve appointment att…

This study is testing a new health system program designed to help more patients with kidney failure start the process for a transplant. It involves 14,000 patients at five major transplant centers and their connected dialysis clinics. The goal is to see if removing system-level …

This study is checking if standard cystic fibrosis (CF) treatments help improve bone density and muscle mass in adults with CF. Researchers are observing 63 adults over 12 to 24 months to see if these treatments can help prevent bone loss and muscle weakness. The goal is to bette…

This early-stage study aimed to test the safety of a supplement called chondroitin sulfate for treating a severe intestinal disease (NEC) in premature, low-birth-weight babies. Researchers wanted to see if this compound, which is found in human breast milk but not most formulas, …

This study is collecting long-term information on a procedure called POEM, which treats achalasia, a condition that makes swallowing difficult. The procedure is done through the mouth without external cuts, aiming to relax a tight muscle in the esophagus. Researchers are tracking…

This study is testing special 'smart' contact lenses that have tiny sensors to measure pressure inside the eye continuously for 24 hours. It involves 120 people, some with glaucoma and some without, to see if these lenses are as accurate and safe as standard clinic measurements. …

This study tests whether showing parents an educational infographic about childhood sleep apnea makes them more likely to discuss symptoms with their child's doctor. Researchers are comparing two groups of parents whose children showed possible symptoms: one group sees the graphi…

This study is testing a new AI tool that uses information from patients' electronic medical records to predict their risk of developing delirium (sudden, severe confusion) after major abdominal surgery. The goal is to see if giving doctors this risk prediction helps them reduce h…

This study is testing a special smart contact lens designed to measure pressure inside a baby's skull without needles or surgery. It aims to see if the lens can accurately detect changes in brain pressure in infants at risk for hydrocephalus (fluid buildup in the brain). Research…

This study is testing a new 3D scanner to see if it can find common tooth problems in children as well as a standard dental check-up. Researchers will compare the scanner's results against a dentist's visual exam for cavities, tooth wear, and fluorosis. The study involves 30 chil…

This program aims to prevent cervical cancer in a region of Kenya by screening adult women and vaccinating young girls against HPV, the virus that causes the cancer. It works directly in communities to overcome barriers like travel distance and lack of education that have kept sc…

This pilot study is testing a new geriatric assessment and management tool designed for older adults living with HIV. The research aims to see if this tailored approach is practical and acceptable for use in HIV clinics and if it can help improve patients' quality of life. The st…

This study aimed to compare two ways of giving oxygen to patients during colonoscopy sedation. Researchers wanted to see if a special nasal mask with air pressure works better than standard nasal tubes at preventing drops in oxygen levels. The trial was designed for adults at hig…

This study is testing whether acupuncture can help manage the chronic pain experienced by people with sickle cell disease. Researchers are comparing traditional needle acupuncture to a needle-free laser version over 10 sessions. They will also use brain scans and other tests to t…

This study aimed to test whether a virtual reality (VR) system could help people recover arm movement after a stroke or other brain injury. The VR system used games based on everyday tasks like cooking or shopping. Eligible participants would have used the VR system twice a week …

This study is testing whether an online group coaching program can help testicular cancer survivors manage their fear of the cancer returning. 70 survivors will be randomly assigned to either a mindfulness-based coaching program or a standard education program, both delivered thr…

This study aimed to test if a combination of two established sedation drugs, remimazolam and fentanyl, could safely put patients to sleep for short dental extractions and allow them to wake up quickly afterward. It planned to enroll healthy adults needing extractions expected to …

This study is testing whether a combination of virtual reality exercises and computer-based brain training can improve memory, attention, and daily life skills in older adults who have both heart failure and mild thinking problems. Researchers will compare the combined approach t…

This study is testing a new teletherapy program called ICARE, designed to help people who have had a traumatic brain injury (TBI). The program aims to improve their ability to recognize others' emotions and show empathy, which can be challenging after a brain injury. The study in…

This study is creating and testing a smartphone app designed to help children and teenagers with spina bifida work with their doctors to set personal goals for managing bladder and bowel incontinence. The app aims to shift the focus from standard medical targets to what matters m…

This study is testing if a gentle electrical stimulation applied to a nerve in the outer ear can influence the main nerve that controls the stomach. Researchers are measuring nerve signals, heart rate, and stomach hormones in people with gastroparesis (a condition that slows stom…

This study is creating a database to collect information on patients who have received a specific heat treatment for pancreatic tumors. The treatment, called endoscopic ultrasound radiofrequency ablation (RFA), uses a scope to deliver heat to destroy tumor tissue. Researchers wil…

This study is testing whether a video decision aid can help patients and doctors have better conversations about colorectal cancer screening. Researchers are working with two Indiana healthcare systems to give 400 eligible patients (ages 45-75) access to the video tool. The goal …

This study aims to understand if gently stimulating a nerve in the outer ear can also activate a deeper nerve that controls stomach function. Researchers are testing this in 30 healthy volunteers by placing electrodes on the ear and neck to measure nerve signals. The goal is to g…

This study is testing whether a special ultraviolet flashlight can safely measure important signaling chemicals in the body without needles or invasive procedures. Researchers will shine the light on participants' skin to see if it can detect nitric oxide, a chemical that helps c…

This study aims to understand how opioid use disorder (OUD) and its treatment medication affect the brain during pregnancy. Researchers will use MRI scans to compare brain connections in 40 pregnant women with OUD to those without OUD. The goal is to gather knowledge that could o…

This project aims to help communities better fight the overdose crisis. It will provide local overdose review teams with a new data dashboard and training, moving them from reviewing single cases to using broader, real-time data. The goal is to help these teams identify key oppor…

This study is collecting information from 500 people who have already had a specific, minimally invasive procedure called TIF to treat their chronic acid reflux (GERD). The goal is to gather data on how patients feel after the procedure to look for trends and help improve care fo…

This study aims to understand if a mild, painless form of brain stimulation can help healthy adults learn a physical movement task in a virtual reality game more quickly. Researchers will have 52 participants play the VR game 'Beat Saber' while some receive real brain stimulation…

This study aims to understand why some patients with advanced melanoma or kidney cancer experience a rare phenomenon where their cancer shrinks or disappears without treatment. Researchers are collecting blood samples and health information from these patients to study their immu…

This study aims to understand if high-protein snack bars make people feel fuller than high-carbohydrate bars. 150 healthy adults will eat each type of bar on separate visits and report their hunger levels. Researchers will then measure how much food participants eat from a buffet…

This study aims to better understand how a stomach stimulator device works for people with gastroparesis, a condition where the stomach empties too slowly. Researchers will place special electrode patches on the necks of 40 patients who already have the device implanted. They wil…

This study aims to understand how a surgically implanted stomach stimulator (GES) affects nerve signals and heart rhythms in people with gastroparesis, a condition where the stomach empties too slowly. Researchers will monitor 300 patients who have or will get the device, using E…

This study aims to understand why some premature babies develop more breathing problems than others during their first year. Researchers are observing about 250 infants born between 24 and 37 weeks to see how their lungs develop. The goal is to identify patterns in lung function …

This study is testing a new, more objective system for deciding which patients get advanced heart failure treatments like transplants and heart pumps. It aims to reduce unfair biases based on a patient's race, ethnicity, or gender. The research will involve over 1,400 participant…

This study aims to develop a non-invasive breath test to measure acidity levels in the airways of people with and without lung disease. Currently, measuring airway pH requires an invasive bronchoscopy procedure. Researchers will test if analyzing nitric oxide in exhaled breath be…

This study is evaluating a new statewide program in Indiana designed to get mental health help to children and teens faster. The program places social workers in 25 pediatric clinics to provide early screening and short-term therapy. Researchers will interview clinic staff and re…