Could CO2 replace dye for heart scans? new study investigates
NCT ID NCT06253884
First seen May 28, 2026 · Last updated Jun 23, 2026 · Updated 7 times
Summary
This pilot study will test whether breathing controlled amounts of carbon dioxide (CO2) can help doctors see blood flow in the heart using MRI, without needing standard contrast dyes. Thirty adults with known or suspected coronary artery disease will take part. The goal is to check if the method is safe, tolerable, and technically feasible.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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IU Health Methodist Hospital
Indianapolis, Indiana, 46202, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Carbon dioxide (CO2) gas delivered via RespirAct device
What this could lead to
If successful, this could lead to a safer, contrast-free way to diagnose blocked arteries in the heart using just CO2 and MRI.
What could go wrong
This is a very early pilot study with only 30 people, so it may not work as hoped or be widely usable. The approach is still experimental and needs much more testing.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.