Heron Therapeutics

This phase 2 trial tests whether a single local dose of HTX-011, a long-acting anesthetic, can reduce pain after bunionectomy better than a placebo. About 70 adults undergoing foot surgery receive either the drug or a saline injection, and their pain is tracked over 24 hours. The…

This study tested a new medicine called HTX-034 to see if it can control pain after bunion surgery better than the standard local anesthetic. 78 adults having bunion surgery received either HTX-034 or the standard treatment. The goal was to measure pain levels and safety over the…

This study tested whether a non-opioid pain regimen, including a long-acting numbing shot (HTX-011) and standard pain relievers like ibuprofen and acetaminophen, could help people avoid opioids after hernia surgery. About 209 adults scheduled for open inguinal hernia repair took …

This study tested three different pain-relief drugs (HTX-011, HTX-002, HTX-009) in 463 adults after open hernia surgery. Participants rated their pain over 24 hours to see how well each drug worked. The goal was to find a safe and effective way to manage pain after this common su…

This phase 3 trial tested a drug called APF530, given as a shot, to prevent nausea and vomiting caused by chemotherapy. Over 1,400 cancer patients took part, comparing APF530 with the standard drug Aloxi. The goal was to see if APF530 could keep patients from vomiting or needing …

This study tested a drug called HTX-011, which combines two pain relievers (bupivacaine and meloxicam), to see if it can control pain better than standard treatments after hernia surgery. 418 adults having open inguinal hernia repair received either HTX-011, a standard painkiller…

This study tested a single dose of an experimental painkiller called HTX-011 given directly into the surgical site during bunionectomy. 78 adults having foot surgery received the drug to see if it could control pain and reduce the need for opioid painkillers. The goal was to impr…

This phase 2 trial tested two experimental drugs, HTX-011 and HTX-002, for pain relief after abdominoplasty (tummy tuck) surgery. 277 adults received an injection of the drug or a placebo. The main goal was to measure pain intensity over the first 24 hours. The study is now compl…

This completed Phase 3 trial tested HTX-011, a combination of bupivacaine and meloxicam, for pain relief after bunionectomy. 412 adults received either HTX-011, a saline placebo, or standard bupivacaine directly into the surgical site. The goal was to see if HTX-011 reduces pain …

This study tested a drug called HTX-011, which combines two pain relievers (bupivacaine and meloxicam), given as a nerve block before breast augmentation surgery. The goal was to see if it reduces pain and the need for opioid painkillers after the operation. The trial involved 24…

This phase 3 trial tested whether a new drug called APF530, given as a shot under the skin, works better than the standard drug ondansetron for preventing nausea and vomiting after strong chemotherapy. About 942 cancer patients took part. The study compared both drugs when combin…

This Phase 2 trial tested a drug called HTX-011 (a mix of bupivacaine and meloxicam) in 63 adults having open inguinal hernia repair. The goal was to see if this painkiller combo, along with other non-opioid medicines, could reduce the need for opioid painkillers after surgery. T…

This study tested a new non-opioid pain medicine called HTX-011 in 116 people having knee replacement surgery. Everyone received the medicine as part of a pain plan that did not include opioids. The goal was to see how well it controlled pain after surgery. The study is complete,…

This study tested a new pain-relieving medicine called HTX-011 in 285 people having knee replacement surgery. The medicine was injected into the surgical area to see if it could reduce pain and the need for strong opioid painkillers. The goal was to find a safer, more effective w…

This study tested an experimental pain medication called HTX-011 in 430 adults recovering from bunion surgery. The goal was to see if it reduces pain better than standard treatments. Participants received the drug locally at the surgery site, and pain levels were tracked for 24 h…

This study looked at whether APF530, a drug for nausea, changes the heart's electrical activity (QT interval) in healthy adults. Fifty-six volunteers received APF530, a placebo, or other comparison drugs in a random order. The goal was to check for heart rhythm risks before the d…