New Non-Opioid painkiller shows promise for knee surgery patients

NCT ID NCT03974932

Completed Symptom relief Sponsor: Heron Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new non-opioid pain medicine called HTX-011 in 116 people having knee replacement surgery. Everyone received the medicine as part of a pain plan that did not include opioids. The goal was to see how well it controlled pain after surgery. The study is complete, and results may help reduce the need for strong opioid painkillers.

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Conditions

The condition(s) this trial relates to.

agnosia pain agnosia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANALGESIA

Contacts and locations

Locations

Endeavor Clinical Trials, LLC.

San Antonio, Texas, 78229, United States
First Surgical Hospital

Bellaire, Texas, 77401, United States
Helen Keller Hospital

Sheffield, Alabama, 35660, United States
Midwest Clinical Research Center, LLC

Dayton, Ohio, 45417, United States
Phoenix Clinical Research, LLC

Tamarac, Florida, 33321, United States
Plano Surgical Hospital

Plano, Texas, 75093, United States

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